[HTML][HTML] Loop-mediated isothermal amplification (LAMP): the better sibling of PCR?
M Soroka, B Wasowicz, A Rymaszewska - Cells, 2021 - mdpi.com
In 1998, when the PCR technique was already popular, a Japanese company called Eiken
Chemical Co., Ltd. designed a method known as the loop-mediated isothermal amplification …
Chemical Co., Ltd. designed a method known as the loop-mediated isothermal amplification …
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) brutally perils physical and
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
Mutations strengthened SARS-CoV-2 infectivity
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity is a major
concern in coronavirus disease 2019 (COVID-19) prevention and economic reopening …
concern in coronavirus disease 2019 (COVID-19) prevention and economic reopening …
[HTML][HTML] Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report
JM Knisely, LE Buyon, R Mandt, R Farkas… - npj Vaccines, 2023 - nature.com
On November 7th and 8th, 2022, The National Institute of Allergy and Infectious Diseases
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …
[HTML][HTML] Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants
SARS-CoV-2 has been mutating since it was first sequenced in early January 2020. Here,
we analyze 45,494 complete SARS-CoV-2 geneome sequences in the world to understand …
we analyze 45,494 complete SARS-CoV-2 geneome sequences in the world to understand …
[HTML][HTML] Amplification-free RNA detection with CRISPR–Cas13
H Shinoda, Y Taguchi, R Nakagawa, A Makino… - Communications …, 2021 - nature.com
CRISPR-based nucleic-acid detection is an emerging technology for molecular diagnostics.
However, these methods generally require several hours and could cause amplification …
However, these methods generally require several hours and could cause amplification …
Current and perspective diagnostic techniques for COVID-19
X Yuan, C Yang, Q He, J Chen, D Yu, J Li… - ACS infectious …, 2020 - ACS Publications
Since late December 2019, the coronavirus pandemic (COVID-19; previously known as
2019-nCoV) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
2019-nCoV) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
The Omicron (B. 1.1. 529) variant of SARS-CoV-2 binds to the hACE2 receptor more strongly and escapes the antibody response: Insights from structural and …
Abstract As SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) continues to
inflict chaos globally, a new variant officially known as B. 1.1. 529 was reported in South …
inflict chaos globally, a new variant officially known as B. 1.1. 529 was reported in South …
[HTML][HTML] Next-generation sequencing (NGS) in COVID-19: a tool for SARS-CoV-2 diagnosis, monitoring new strains and phylodynamic modeling in molecular …
This review discusses the current testing methodologies for COVID-19 diagnosis and
explores next-generation sequencing (NGS) technology for the detection of SARS-CoV-2 …
explores next-generation sequencing (NGS) technology for the detection of SARS-CoV-2 …
[HTML][HTML] Prediction and mitigation of mutation threats to COVID-19 vaccines and antibody therapies
Antibody therapeutics and vaccines are among our last resort to end the raging COVID-19
pandemic. They, however, are prone to over 5000 mutations on the spike (S) protein …
pandemic. They, however, are prone to over 5000 mutations on the spike (S) protein …