[HTML][HTML] Potential treatments for COVID-19; a narrative literature review

A Rismanbaf - Archives of academic emergency medicine, 2020 - ncbi.nlm.nih.gov
SARS-CoV-2 is a newly emerging human infectious coronavirus that causes COVID-19,
which has been recognized as a pandemic by the World Health Organization (WHO) on …

Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies

G Galindez, J Matschinske, TD Rose… - Nature Computational …, 2021 - nature.com
Responding quickly to unknown pathogens is crucial to stop uncontrolled spread of
diseases that lead to epidemics, such as the novel coronavirus, and to keep protective …

Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents

V Mody, J Ho, S Wills, A Mawri, L Lawson… - Communications …, 2021 - nature.com
Emerging outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection is a major threat to public health. The morbidity is increasing due to lack of SARS …

Structural and evolutionary analysis indicate that the SARS-CoV-2 Mpro is a challenging target for small-molecule inhibitor design

M Bzówka, K Mitusińska, A Raczyńska… - International Journal of …, 2020 - mdpi.com
The novel coronavirus whose outbreak took place in December 2019 continues to spread at
a rapid rate worldwide. In the absence of an effective vaccine, inhibitor repurposing or de …

Virtual screening, molecular dynamics and structure–activity relationship studies to identify potent approved drugs for Covid-19 treatment

MM Rahman, T Saha, KJ Islam, RH Suman… - Journal of …, 2021 - Taylor & Francis
Computer-aided drug screening by molecular docking, molecular dynamics (MD) and
structural–activity relationship (SAR) can offer an efficient approach to identify promising …

[HTML][HTML] Information technology in emergency management of COVID-19 outbreak

A Asadzadeh, S Pakkhoo, MM Saeidabad… - Informatics in medicine …, 2020 - Elsevier
Emergency management of the emerging infectious disease outbreak is critical for public
health threats. Currently, control of the COVID-19 outbreak is an international concern and …

Repurposing of the approved small molecule drugs in order to inhibit SARS-CoV-2 S protein and human ACE2 interaction through virtual screening approaches

H Kalhor, S Sadeghi, H Abolhasani… - Journal of …, 2022 - Taylor & Francis
Most recently, the new coronavirus (SARS-CoV-2) has been recognized as a pandemic by
the World Health Organization (WHO) while this virus shares substantial similarity with …

Study of combining virtual screening and antiviral treatments of the Sars-CoV-2 (Covid-19)

E Khodadadi, P Maroufi, E Khodadadi, I Esposito… - Microbial …, 2020 - Elsevier
The recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 and
causing the respiratory tract disease COVID-19 has reached worldwide resonance and a …

Aloin isoforms (A and B) selectively inhibits proteolytic and deubiquitinating activity of papain like protease (PLpro) of SARS-CoV-2 in vitro

DSM Lewis, J Ho, S Wills, A Kawall, A Sharma… - Scientific reports, 2022 - nature.com
The most common host entry point of human adapted coronaviruses (CoV) including SARS-
CoV-2 is through the initial colonization in the nostril and mouth region which is responsible …

Therapeutics for COVID-19: from computation to practices—where we are, where we are heading to

PK Ojha, S Kar, JG Krishna, K Roy, J Leszczynski - Molecular Diversity, 2021 - Springer
Abstract After the 1918 Spanish Flu pandemic caused by the H1N1 virus, the recent
coronavirus disease 2019 (COVID-19) brought us to the time of serious global health …