In spite of current influenza vaccines being immunogenic, evolution of the influenza virus
can reduce efficacy and so influenza remains a major threat to public health. One approach …

Vaccination is the most effective method to prevent influenza infection. However, current
influenza vaccines have several limitations. Relatively long production times, limited vaccine …

Background New influenza vaccines eliciting more effective protection are needed,
particularly for the elderly who paid a large and disproportional toll of hospitalization and …

Influenza virus infections pose a significant threat to public health due to annual seasonal
epidemics and occasional pandemics. Influenza is also associated with significant economic …

Introduction Older adults are prioritized for influenza vaccination but also have lowered
antibody responses to the vaccine. Higher-doses of influenza antigen may increase immune …

Infectious diseases are a major cause for morbidity and mortality in the older population.
Demographic changes will lead to increasing numbers of older persons over the next …

Background Influenza is associated with a high mortality and morbidity in older adults.
Vaccination remains the most effective method of preventing influenza and its …

Background Recently, lower estimates of influenza vaccine effectiveness (VE) against A
(H3N2) virus illness among those vaccinated during the previous season or multiple …

Abstract The International Society for Influenza and other Respiratory Virus Diseases held its
5th Antiviral Group (isirv-AVG) Conference in Shanghai, China, in conjunction with the …

Fifteen meta-analyses have been published between 1995 and 2011 to evaluate the
efficacy/effectiveness and harms of diverse influenza vaccines—seasonal, H5N1 and 2009 …