Immune-mediated attenuation of influenza illness after infection: opportunities and challenges

MM Patel, IA York, AS Monto, MG Thompson… - The Lancet …, 2021 - thelancet.com
Sterilising immunity that blocks infection for life, and thus prevents illness after infection, is
the ultimate goal for vaccines. Neither influenza infection nor vaccination provide sterilising …

Review of influenza virus vaccines: the qualitative nature of immune responses to infection and vaccination is a critical consideration

L Chan, K Alizadeh, K Alizadeh, F Fazel, JE Kakish… - Vaccines, 2021 - mdpi.com
Influenza viruses have affected the world for over a century, causing multiple pandemics.
Throughout the years, many prophylactic vaccines have been developed for influenza; …

Vaccine effectiveness against life-threatening influenza illness in US children

SM Olson, MM Newhams, NB Halasa… - Clinical Infectious …, 2022 - academic.oup.com
Background Predominance of 2 antigenically drifted influenza viruses during the 2019–2020
season offered an opportunity to assess vaccine effectiveness against life-threatening …

Maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in infants

LC Sahni, SM Olson, NB Halasa, LS Stewart… - JAMA …, 2024 - jamanetwork.com
Importance Influenza virus infection during pregnancy is associated with severe maternal
disease and may be associated with adverse birth outcomes. Inactivated influenza vaccine …

Realizing the potential of maternal influenza vaccination

E Azziz-Baumgartner, L Grohskopf, M Patel - Jama, 2021 - jamanetwork.com
Influenza viruses cause substantial morbidity and mortality in pregnant women and
neonates worldwide annually, with higher incidence during pandemics. 1, 2 To reduce …

[HTML][HTML] Recent advances in influenza vaccines

G Pawelec, J McElhaney - F1000Research, 2020 - ncbi.nlm.nih.gov
Seasonal influenza remains a major public health problem, responsible for hundreds of
thousands of deaths every year, mostly of elderly people. Despite the wide availability of …

Antibody response and protection after receipt of inactivated influenza vaccine: a systematic review

DJ Wall, MM Patel, JR Chung, B Lee, FS Dawood - Pediatrics, 2021 - publications.aap.org
OBJECTIVE: To systematically review studies comparing vaccine effectiveness (VE) and
immunogenicity after 1 or 2 doses of inactivated influenza vaccine (IIV) in children. DATA …

Influenza A (H3N2) Antibody Responses to Standard-Dose Versus Enhanced Influenza Vaccine Immunogenicity in Older Adults and Prior Season's Vaccine Status

S Zhong, TWY Ng, DM Skowronski… - The Journal of …, 2023 - academic.oup.com
Background Annual influenza vaccination is recommended for older adults but repeated
vaccination with standard-dose influenza vaccine has been linked to reduced …

[HTML][HTML] Antibody responses against heterologous A/H5N1 strains for an MF59-adjuvanted cell culture–derived A/H5N1 (aH5N1c) influenza vaccine in healthy …

P Chanthavanich, E Versage, E Van Twuijver… - Vaccine, 2021 - Elsevier
Background Vaccines are the main prophylactic measure against pandemic influenza.
Adjuvanted, cell culture–derived vaccines, which are not subject to limitations of egg-based …

Cord blood-based approach to assess candidate vaccine adjuvants designed for neonates and infants

D Tokuhara, N Hikita - Vaccines, 2021 - mdpi.com
Neonates and infants are particularly susceptible to infections, for which outcomes tend to
be severe. Vaccination is a key strategy for preventing infectious diseases, but the protective …