Does the performance of an amorphous solid dispersion rely on having 100% amorphous
content? What specifications are appropriate for crystalline content within an amorphous …

Recent work has highlighted that amorphous solid dispersions (ASDs) containing
delamanid (DLM) and an enteric polymer, hypromellose phthalate (HPMCP), appear to be …

Atomic layer coating (ALC) is emerging as a particle engineering strategy to inhibit surface
crystallization of amorphous solid dispersions (ASDs). In this study, we turn our attention to …

As a promising strategy, amorphous solid dispersion (ASD) technology has been widely
studied and employed. However, moisture affects the physical stability of ASD, leading to …

Pharmaceutical products represent a meaningful target for sustainability improvement and
emissions reduction. It is proposed here that rethinking the standard, and often linear …

Abstract Functional coatings on Active Pharmaceutical Ingredients (API) are used in the
pharmaceutical industry to enhance mechanical strength, enable controlled release, taste …

Inhibiting surface crystallization is an interesting strategy to enhance the physical stability of
amorphous solid dispersions (ASDs), still preserving high drug loads. The aim of this study …

The effects of atomic layer (ALC) coating on physical properties and storage stability were
examined in solid powders containing myoglobin, a model protein. Powders containing …

The number of drug molecules that show poor aqueous solubility and low dissolution rate
has significantly increased during the past two decades, resulting in low oral bioavailability …