[HTML][HTML] Therapeutic potential of ginger against COVID-19: Is there enough evidence?

A Jafarzadeh, S Jafarzadeh, M Nemati - Journal of Traditional Chinese …, 2021 - Elsevier
In addition to the respiratory system, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …

[HTML][HTML] An update review of emerging small-molecule therapeutic options for COVID-19

D Tian, Y Liu, C Liang, L Xin, X Xie, D Zhang… - Biomedicine & …, 2021 - Elsevier
The SARS-CoV-2 outbreak and pandemic that began near the end of 2019 has posed a
challenge to global health. At present, many candidate small-molecule therapeutics have …

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

Ligand-based quantitative structural assessments of SARS-CoV-2 3CLpro inhibitors: An analysis in light of structure-based multi-molecular modeling evidences

N Adhikari, S Banerjee, SK Baidya, B Ghosh… - Journal of Molecular …, 2022 - Elsevier
Due to COVID-19, the whole world is undergoing a devastating situation, but treatment with
no such drug candidates still has been established exclusively. In that context, 69 diverse …

[HTML][HTML] Comprehensive in silico discovery of c-Src tyrosine kinase inhibitors in cancer treatment: A unified approach combining pharmacophore modeling, 3D QSAR …

S Khamouli, MT Rehman, N Zegheb, A Hussain… - Journal of King Saud …, 2024 - Elsevier
Abstract Objective To investigate c-Src, a non-receptor tyrosine kinase dysregulated in
various cancer types including colon, breast, and pancreatic cancers, as a potential drug …

[HTML][HTML] Biomarker Quantification, Spectroscopic, and Molecular Docking Studies of the Active Compounds Isolated from the Edible Plant Sisymbrium irio L.

SM Al-Massarani, LS Aldurayhim, IA Alotaibi… - Pharmaceuticals, 2023 - mdpi.com
Phytochemical investigation of the ethanolic extract of the aerial parts of Sisymbrium irio L.
led to the isolation of four unsaturated fatty acids (1–4), including a new one (4), and four …

[HTML][HTML] A closer look at dexamethasone and the SARS-CoV-2-induced cytokine storm: in silico insights of the first life-saving COVID-19 drug

P Morgan, SJ Arnold, NW Hsiao, CW Shu - Antibiotics, 2021 - mdpi.com
The term cytokine storm refers to an uncontrolled overproduction of soluble inflammatory
markers known as cytokines and chemokines. Autoimmune destruction of the lungs …

Structure based drug designing approaches in SARS-CoV-2 spike inhibitor design

A Shanmugam, A Venkattappan… - Current Topics in …, 2022 - ingentaconnect.com
The COVID-19 outbreak and the pandemic situation have hastened the research community
to design a novel drug and vaccine against its causative organism, the SARS-CoV-2. The …

AQP4-DARPin1: A Chimeric Antigen Based on Scaffold Protein DARPin for Efficient Detection of AQP4-IgG in NMOSD

X Wang, S Ma, Y Bai, X Wu, F Ji, L Jia - Biochemistry, 2024 - ACS Publications
AQP4-IgG is an autoantibody associated with neuromyelitis optica spectroscopic disorder
(NMOSD), a central nervous system inflammatory disease that requires early diagnosis and …

[HTML][HTML] A review of in silico research, SARS-CoV-2, and neurodegeneration: focus on papain-like protease

AS Rieder, BF Deniz, CA Netto, ATS Wyse - Neurotoxicity Research, 2022 - Springer
Since the appearance of SARS-CoV-2 and the COVID-19 pandemic, the search for new
approaches to treat this disease took place in the scientific community. The in silico …