[HTML][HTML] Advances in the development of amorphous solid dispersions: The role of polymeric carriers
J Zhang, M Guo, M Luo, T Cai - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …
Fed-and fasted-state performance of pretomanid amorphous solid dispersions formulated with an enteric polymer
HT Nguyen, T Van Duong, S Jaw-Tsai… - Molecular …, 2023 - ACS Publications
Weakly acid polymers with pH-responsive solubility are being used with increasing
frequency in amorphous solid dispersion (ASD) formulations of drugs with low aqueous …
frequency in amorphous solid dispersion (ASD) formulations of drugs with low aqueous …
[HTML][HTML] A comparison of spray-drying and co-precipitation for the generation of amorphous solid dispersions (ASDS) of hydrochlorothiazide and simvastatin
M Myślińska, MW Stocker, S Ferguson… - Journal of Pharmaceutical …, 2023 - Elsevier
Co-processing of APIs, the practice of creating multi-component APIs directly in chemical
processing facilities used to make drug substance, is gaining increased attention with a view …
processing facilities used to make drug substance, is gaining increased attention with a view …
Drug aggregation of sparingly-soluble ionizable drugs: molecular dynamics simulations of papaverine and prostaglandin F2α
Aggregation in aqueous solution can have important implications on both the in vivo
exposure of a drug and its pharmaceutical manufacturability. However, the drug aggregates …
exposure of a drug and its pharmaceutical manufacturability. However, the drug aggregates …
Microfluidic Particle Engineering of Hydrophobic Drug with Eudragit E100─ Bridging the Amorphous and Crystalline Gap
Co-processing active pharmaceutical ingredients (APIs) with excipients is a promising
particle engineering technique to improve the API physical properties, which can lead to …
particle engineering technique to improve the API physical properties, which can lead to …
Poly(vinylpyridine-co-vinylpyridine N-oxide) Excipients Mediate Rapid Dissolution and Sustained Supersaturation of Posaconazole Amorphous Solid Dispersions
The chemical structure of excipients molecularly mixed in an amorphous solid dispersion
(ASD) has a significant impact on properties of the ASD including dissolution behavior …
(ASD) has a significant impact on properties of the ASD including dissolution behavior …