The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately
assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine …

The safety of vaccines is a critical factor in maintaining public trust in national vaccination
programs. Vaccines are recommended for children, adults and elderly subjects and have to …

The traditional platform of using embryonated chicken eggs for the production of influenza
vaccines has several drawbacks including the inability to meet the volume of required doses …

Vaccination remains the most effective prophylactic intervention for infectious disease in the
healthcare professional's toolkit. However, the efficacy and effectiveness of vaccines …

A potentially deadly A/H7N9 avian-origin influenza virus is currently the cause of an ongoing
outbreak in China. Preparedness plans have thus been initiated to preempt the spread of …

In the RV144 vaccine trial, IgG responses against the HIV envelope variable loops 1 and 2
(V1V2) were associated with decreased HIV acquisition risk. We previously reported that …

Background During development of an A/H1N1 pandemic influenza vaccine, this study was
performed to identify the antigen and adjuvant content which would provide optimal antibody …

Modern cell culture-based technology eliminates vaccine manufactures reliance on
embryonated chicken eggs, which may become compromised during an avian influenza …

Objectives This study was designed to identify the optimal dose of an MF59®-adjuvanted,
monovalent, A/H1N1 influenza vaccine in healthy paediatric subjects. Methods Subjects …

Abstract Background A/H5N1 influenza viruses have high pandemic potential; consequently,
vaccines need to be produced rapidly. MF59® adjuvant reduces the antigen required per …