Objective: To assess the occurrence of narcolepsy after influenza vaccines used in the
United States that contained the influenza A (H1N1) pdm09 virus strain. Methods: A …

Seasonal influenza virus vaccines are generally effective at preventing disease, but need to
be well matched to circulating virus strains for maximum benefit. Influenza viruses constantly …

Inactivated influenza vaccines are produced every year to fight against the seasonal
epidemics of influenza. Despite the nonoptimal coverage, even in subjects at risk like the …

Highlights•Reverse, structural and synthetic vaccinology to accelerate novel vaccine
design.•Systems analysis of multiparametric data to predict reactogenicity and …

Many pathogenic viral pandemics have caused threats to global health; the COVID-19
pandemic is the latest. Its transmission is growing exponentially all around the globe, putting …

Mass vaccination has saved millions of human lives and improved the quality of life in both
developing and developed countries. The emergence of new pathogens and inadequate …

Objectives We previously described the Phase I‐II evaluation of SARS‐CoV‐2 recombinant
protein candidate vaccine, CoV2‐PreS‐dTM, with AF03‐or AS03‐adjuvant systems …

The coronavirus disease (COVID-19) pandemic poses serious global health concerns with
the continued emergence of new variants. The periodic outbreak of novel emerging and re …

ABSTRACT AF03 is a squalene‐based emulsion adjuvant that is present in the adjuvanted
pandemic influenza vaccine, Humenza™. In this report, we describe the design and …

Other than clean drinking water, vaccines have been the most effective public health
intervention in human history, yet their full potential is still untapped. To date, vaccine …