The direct functionalization of C (sp3)–H bonds represents one of the most investigated
approaches to develop new synthetic methodology. Among the available strategies for …

The C–H functionalization of silyl ethers via carbene-induced C–H insertion represents an
efficient synthetic disconnection strategy. In this work, site-and stereoselective C (sp3)–H …

The chemical sciences are witnessing an influx of statistics into the catalysis literature.
These developments are propelled by modern technological advancements that are leading …

A special type of C–H functionalization can be achieved through C–H insertion combined
with Cope rearrangement (CHCR) in the presence of dirhodium catalysts. This type of …

A detailed study on the C (sp3)–H bond oxygenation reactions with H2O2 catalyzed by the
[Mn (OTf) 2 (TIPSmcp)] complex at methylenic sites of cycloalkyl and 1-alkyl substrates …

Machine learning can make a strong contribution to accelerating the discovery of transition
metal complexes (TMC). These compounds will play a key role in the development of new …

Chiral ligands are important components in asymmetric homogeneous catalysis, but their
synthesis and screening can be both time-consuming and resource-intensive. Data-driven …

The exponential proliferation of conformers makes it impossible to examine the entire
population in most systems. Controlling conformational ensembles is thus pivotal in many …

Selective functionalization of non‐activated C (sp3)− H bonds is a major challenge in
chemistry, so functional groups are often used to enhance reactivity. Here, we present a gold …

Interactions between catalysts and substrates can be highly complex and dynamic, often
complicating the development of models to either predict or understand such processes. A …