Despite widespread influenza vaccination programs, influenza remains a major cause of
morbidity and mortality in older adults. Age-related changes in multiple aspects of the …

Infectious diseases are a major cause for morbidity and mortality in the older population.
Demographic changes will lead to increasing numbers of older persons over the next …

Viral respiratory infections are risk factors for cardiovascular disease (CVD). Underlying
CVD is also associated with an increased risk of complications following viral respiratory …

The development of vaccines, which prime the immune system to respond to future
infections, has led to global declines in morbidity and mortality from dreadful infectious …

Aim Adjuvanted influenza vaccines can overcome the poor antibody response of
conventional non-adjuvanted vaccines in the elderly. We evaluated the immunogenicity …

Background The effectiveness of standard, egg-derived quadrivalent influenza vaccines
(IIV4) may be reduced in adults≥ 65 years of age, largely because of immunosenescence …

Introduction The influenza vaccine is less immunogenic in older than younger adults, and
the duration of protection is unclear. Determining if protection persists beyond a typical …

Background A number of enhanced influenza vaccines have been developed for use in
older adults, including high-dose, MF59-adjuvanted, and intradermal vaccines. Methods We …

Inactivated influenza vaccines are produced every year to fight against the seasonal
epidemics of influenza. Despite the nonoptimal coverage, even in subjects at risk like the …

Background Accurate reporting on sex and gender in health research is integral to ensuring
that health interventions are safe and effective. In Canada and internationally, governments …