Messenger RNA (mRNA)‐based therapy has emerged as a powerful, safe, and rapidly
scalable therapeutic approach that involves technologies for both mRNA itself and the …

mRNA vaccines have evolved as promising cancer therapies. These vaccines can encode
tumor-allied antigens, thus enabling personalized treatment approaches. They can also …

Introduction Tumors pose a significant global economic and health burden, with
conventional cancer treatments lacking tumor specificity, leading to limited efficiency and …

RNA‐based therapeutics have emerged as a promising strategy for cancer immunotherapy,
encompassing the silencing of immune checkpoint genes, chimeric antigen receptor T (CAR …

The success of lipid nanoparticles (LNPs) in treating COVID-19 promotes further research of
mRNA vaccines for cancer vaccination. Aiming at overcoming the constraints of currently …

Research into mRNA vaccines is advancing rapidly, with proven efficacy against
coronavirus disease 2019 and promising therapeutic potential against a variety of solid …

The mRNA-based COVID-19 vaccine has been a tremendous success, instilling hope for the
treatment of other malignant diseases. However, the current commercially available mRNA …

Therapeutic cancer vaccines have shown promising efficacy in helping immunotherapy for
cancer patients, but the systematic characterization of the clinical application and the …

Introduction Colorectal cancer (CRC) is the second most lethal malignancy worldwide.
Immune checkpoint inhibitors (ICIs) benefit only 15% of patients with mismatch repair …

The emergence of tumors associated with defects in immune surveillance often involve the
impairment of key functions of T lymphocytes. Therefore, several anticancer …