[HTML][HTML] Divergent functions of NLRP3 inflammasomes in cancer: a review

A Shadab, M Mahjoor, M Abbasi-Kolli… - Cell Communication and …, 2023 - Springer
The cancer is a serious health problem, which is The cancer death rate (cancer mortality) is
158.3 per 100,000 men and women per year (based on 2013–2017 deaths). Both clinical …

[HTML][HTML] Organosulfur compounds: A review of their anti-inflammatory effects in human health

RT Ruhee, LA Roberts, S Ma, K Suzuki - Frontiers in nutrition, 2020 - frontiersin.org
Phytonutrients are widely recognized for providing protective human health benefits. Among
the phytonutrients, epidemiological and experimental studies show that dietary organosulfur …

Recent insights on modulation of inflammasomes by adipokines: a critical event for the pathogenesis of obesity and metabolism-associated diseases

DV Pham, PH Park - Archives of pharmacal research, 2020 - Springer
Aberrant production of adipokines, a group of adipocytes-derived hormones, is considered
one of the most important pathological characteristics of obesity. In individuals with obesity …

[HTML][HTML] NLRP3 inflammasome: a new therapeutic target for high-risk reproductive disorders?

F Zhou, C Li, SY Zhang - Chinese medical journal, 2021 - journals.lww.com
The NOD-like receptor protein 3 (NLRP3) inflammasome is a key regulator of the host's
immune response, and many immune and metabolic disorders are linked to its activation …

[HTML][HTML] Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity

H Ahn, GS Lee - Scientific Reports, 2020 - nature.com
Riboflavin is commonly taken as a nutritional supplement, and it converts to coenzymes
during the process of energy production from carbohydrates, fats, and proteins. Although …

[HTML][HTML] Korean Red Ginseng, a regulator of NLRP3 inflammasome, in the COVID-19 pandemic

EM Jung, GS Lee - Journal of ginseng research, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) exhibits various symptoms, ranging from
asymptomatic to severe pneumonia or death. The major features of patients in severe …

[HTML][HTML] Lower temperatures exacerbate NLRP3 inflammasome activation by promoting monosodium urate crystallization, causing gout

H Ahn, G Lee, GS Lee - Cells, 2021 - mdpi.com
Gout is a recurrent and chronic form of arthritis caused by the deposition of monosodium
urate (MSU) crystals in the joints. Macrophages intake MSU crystals, the trigger for NLRP3 …

Effects of treatment with gold nanoparticles in a model of acute pulmonary inflammation induced by lipopolysaccharide

DP dos Santos Haupenthal, C Mendes… - … Research Part A, 2020 - Wiley Online Library
The bacterial lipopolysaccharide (LPS) is a highly toxic molecule derived from the outer
membrane of gram‐negative bacteria. LPS endotoxin affects the lungs and is used as a …

[HTML][HTML] Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo

HYP Lam, TR Liang, SY Peng - PLoS neglected tropical diseases, 2021 - journals.plos.org
Schistosomiasis is second only to malaria as the most devastating parasitic disease in the
world. It is caused by the helminths Schistosoma mansoni (S. mansoni), S. haematobium, or …

Analysis of necroptosis and its association with pyroptosis in organ damage in experimental pulmonary arterial hypertension

I Jarabicová, C Horváth, E Veľasová… - Journal of Cellular …, 2022 - Wiley Online Library
In this study, a role of cell loss due to necroptosis and its linkage with pyroptosis in organ
damage under the conditions of pulmonary arterial hypertension (PAH) was examined …