Proof-of-concept in developing a 45% drug loaded amorphous nanoparticle formulation
Amorphous solid dispersion (ASD) is an enabling approach utilized to deliver poorly soluble
compounds. ASDs can spontaneously generate drug-rich amorphous nanoparticles upon …
compounds. ASDs can spontaneously generate drug-rich amorphous nanoparticles upon …
[HTML][HTML] Nanoparticle delivery of TFOs is a novel targeted therapy for HER2 amplified breast cancer
X Yang, Y Xu, J Fu, Z Shen - BMC cancer, 2023 - Springer
Abstract Purpose The human EGFR2 (HER2) signaling pathway is one of the most actively
studied targets in cancer transformation research. Ttriplex-forming oligonucleotides (TFOs) …
studied targets in cancer transformation research. Ttriplex-forming oligonucleotides (TFOs) …
Design of Redispersible High-Drug-Load Amorphous Formulations: Impact of Ionic vs Nonionic Surfactants on Processing and Performance
M Yu, HS Oberoi, HS Purohit, CA Fowler… - Molecular …, 2023 - ACS Publications
Amorphous solid dispersions (ASDs) are an enabling formulation approach used to
enhance bioavailability of poorly water-soluble molecules in oral drug products. Drug-rich …
enhance bioavailability of poorly water-soluble molecules in oral drug products. Drug-rich …