Microneedle system for tissue engineering and regenerative medicine

Y Zhang, Y Xu, H Kong, J Zhang, HF Chan… - …, 2023 - Wiley Online Library
Global increasing demand for high life quality and length facilitates the development of
tissue engineering and regenerative medicine, which apply multidisciplinary theories and …

Vat photopolymerization 3D printing for advanced drug delivery and medical device applications

X Xu, A Awad, P Robles-Martinez, S Gaisford… - Journal of Controlled …, 2021 - Elsevier
Abstract Three-dimensional (3D) printing is transforming manufacturing paradigms within
healthcare. Vat photopolymerization 3D printing technology combines the benefits of high …

Blue-ringed octopus-inspired microneedle patch for robust tissue surface adhesion and active injection drug delivery

Z Zhu, J Wang, X Pei, J Chen, X Wei, Y Liu, P Xia… - Science …, 2023 - science.org
Intratissue topical medication is important for the treatment of cutaneous, mucosal or
splanchnic diseases. However, penetrating surface barriers to providing adequate and …

Advances in antimicrobial microneedle patches for combating infections

R Jamaledin, CKY Yiu, EN Zare, LN Niu… - Advanced …, 2020 - Wiley Online Library
Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

[HTML][HTML] Challenges and recent progress in oral drug delivery systems for biopharmaceuticals

B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

[HTML][HTML] A comprehensive review of microneedles: Types, materials, processes, characterizations and applications

FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …

Hydrogel‐forming microneedles: current advancements and future trends

JG Turner, LR White, P Estrela… - Macromolecular …, 2021 - Wiley Online Library
In this focused progress review, the recent developments and trends of hydrogel‐forming
microneedles (HFMs) and potential future directions are presented. Previously …

[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

Q Zhu, Z Chen, PK Paul, Y Lu, W Wu, J Qi - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …

Materials for oral delivery of proteins and peptides

TD Brown, KA Whitehead, S Mitragotri - Nature Reviews Materials, 2020 - nature.com
Throughout history, oral administration has been regarded as the most convenient mode of
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …

Microneedles for painless transdermal immunotherapeutic applications

H Amani, MA Shahbazi, C D'Amico, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …