[PDF][PDF] Rigidity and flexibility of pyrazole, s-triazole, and v-triazole derivative of chloroquine as potential therapeutic against COVID-19
We [1, 2] and others [3- 5] have been interested in designing and making new molecules
that have biological activities, medicinal uses, coordination behaviors [6- 8] and studying …
that have biological activities, medicinal uses, coordination behaviors [6- 8] and studying …
[HTML][HTML] Combination and tricombination therapy to destabilize the structural integrity of COVID-19 by some bioactive compounds with antiviral drugs: insights from …
HRA El-Mageed, DA Abdelrheem, SA Ahmed… - Structural …, 2021 - Springer
Abstract Recently, the SARS-CoV-2 (COVID-19) pandemic virus has been spreading
throughout the world. Until now, no certified drugs have been discovered to efficiently inhibit …
throughout the world. Until now, no certified drugs have been discovered to efficiently inhibit …
[HTML][HTML] DFT and molecular docking study of chloroquine derivatives as antiviral to coronavirus COVID-19
O Noureddine, N Issaoui, O Al-Dossary - Journal of King Saud University …, 2021 - Elsevier
The recently emerged COVID-19 virus caused hundreds of thousands of deaths and
instigated a widespread fear, threatening the world's most advanced health security. In …
instigated a widespread fear, threatening the world's most advanced health security. In …
Screening of Chloroquine, Hydroxychloroquine and its derivatives for their binding affinity to multiple SARS-CoV-2 protein drug targets
M Nimgampalle, V Devanathan… - Journal of Biomolecular …, 2021 - Taylor & Francis
Recently Chloroquine and its derivative Hydroxychloroquine have garnered enormous
interest amongst the clinicians and health authorities' world over as a potential treatment to …
interest amongst the clinicians and health authorities' world over as a potential treatment to …
Identification of 1, 2, 3-triazole-phthalimide derivatives as potential drugs against COVID-19: a virtual screening, docking and molecular dynamic study
VN Holanda, EMA Lima, WV Silva… - Journal of …, 2022 - Taylor & Francis
In this work we aimed to perform an in silico predictive screening, docking and molecular
dynamic study to identify 1, 2, 3-triazole-phthalimide derivatives as drug candidates against …
dynamic study to identify 1, 2, 3-triazole-phthalimide derivatives as drug candidates against …
[HTML][HTML] Investigation of Some Antiviral N-Heterocycles as COVID 19 Drug: Molecular Docking and DFT Calculations
The novel coronavirus, COVID-19, caused by SARS-CoV-2, is a global health pandemic that
started in December 2019. The effective drug target among coronaviruses is the main …
started in December 2019. The effective drug target among coronaviruses is the main …
In-silico strategies for probing chloroquine based inhibitors against SARS-CoV-2
The global health emergency of novel COVID-19 is due to severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2). Currently there are no approved drugs for the …
syndrome coronavirus-2 (SARS-CoV-2). Currently there are no approved drugs for the …
New anti-viral drugs for the treatment of COVID-19 instead of favipiravir
The SARS-CoV-2 virus is a major problem in the world right now. Currently, all the attention
of research centers and governments globally are focused on the investigation of …
of research centers and governments globally are focused on the investigation of …
Approach to the mechanism of action of hydroxychloroquine on SARS-CoV-2: a molecular docking study
I Celı̇k, A Onay-Besı̇kcı̇… - Journal of Biomolecular …, 2021 - Taylor & Francis
We aimed to analyze the interactions of both hydroxychloroquine and chloroquine with
SARS-CoV-2 and identify their possible role for the prevention/treatment of COVID-19 by …
SARS-CoV-2 and identify their possible role for the prevention/treatment of COVID-19 by …
Current status and strategic possibilities on potential use of combinational drug therapy against COVID-19 caused by SARS-CoV-2
The spread of new coronavirus infection starting December 2019 as novel SARS-CoV-2,
identified as the causing agent of COVID-19, has affected all over the world and been …
identified as the causing agent of COVID-19, has affected all over the world and been …