[HTML][HTML] Microarray patches enable the development of skin-targeted vaccines against COVID-19
E Korkmaz, SC Balmert, TL Sumpter, CD Carey… - Advanced drug delivery …, 2021 - Elsevier
The COVID-19 pandemic is a serious threat to global health and the global economy. The
ongoing race to develop a safe and efficacious vaccine to prevent infection by SARS-CoV-2 …
ongoing race to develop a safe and efficacious vaccine to prevent infection by SARS-CoV-2 …
Microarray patches: scratching the surface of vaccine delivery
Introduction Microneedles are emerging as a promising technology for vaccine delivery, with
numerous advantages over traditional needle and syringe methods. Preclinical studies have …
numerous advantages over traditional needle and syringe methods. Preclinical studies have …
Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than
160 million people and resulted in more than 3.3 million deaths, and despite the availability …
160 million people and resulted in more than 3.3 million deaths, and despite the availability …
COVID-19 vaccines and the skin: the landscape of cutaneous vaccine reactions worldwide
Q Sun, R Fathy, DE McMahon… - Dermatologic clinics, 2021 - derm.theclinics.com
As of April 22, 2021, the novel coronavirus disease 2019 (COVID-19) has sickened more
than 142 million people and taken more than 3 million lives worldwide. 1 Although …
than 142 million people and taken more than 3 million lives worldwide. 1 Although …
A Single‐Administration Microneedle Skin Patch for Multi‐Burst Release of Vaccine against SARS‐CoV‐2
The necessity for multiple injections and cold‐chain storage has contributed to suboptimal
vaccine utilization, especially in pandemic situations. Thermally‐stable and single …
vaccine utilization, especially in pandemic situations. Thermally‐stable and single …
[HTML][HTML] The skin as a critical window in unveiling the pathophysiologic principles of COVID-19
C Magro, G Nuovo, JJ Mulvey, J Laurence, J Harp… - Clinics in …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of
coronavirus disease 2019 (COVID-19), is a single-stranded RNA virus whose sequence is …
coronavirus disease 2019 (COVID-19), is a single-stranded RNA virus whose sequence is …
Engineering immunity via skin-directed drug delivery devices
Extensive research is underway to discover a safe and effective vehicle to deliver the
vaccines at the desired cutaneous site. These efforts majorly comprise the development of a …
vaccines at the desired cutaneous site. These efforts majorly comprise the development of a …
Vaccination into the dermal compartment: techniques, challenges, and prospects
J Hettinga, R Carlisle - Vaccines, 2020 - mdpi.com
In 2019, an 'influenza pandemic'and 'vaccine hesitancy'were listed as two of the top 10
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …
Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
E Kim, G Erdos, S Huang, TW Kenniston, SC Balmert… - …, 2020 - thelancet.com
Background Coronaviruses pose a serious threat to global health as evidenced by Severe
Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and …
Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and …
Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model
Background Over 14 million people die each year from infectious diseases despite
extensive vaccine use. The needle and syringe—first invented in 1853—is still the primary …
extensive vaccine use. The needle and syringe—first invented in 1853—is still the primary …
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