Amorphization is one of the most effective pharmaceutical approaches to enhance the
dissolution and oral bioavailability of poorly water-soluble drugs. In recent years, amorphous …

Dissolution test is an extremely valuable and powerful tool in understanding the parameters
that control dissolution of amorphous formulations as well as in revealing supersaturation …

Out of many, one of the most promising strategies to improve the oral bioavailability of poorly
water-soluble drugs is to develop amorphous solid dispersions. Reduction in drug particle …

The combination of a rapidly dissolving and supersaturating “spring” with a precipitation
retarding “parachute” has often been pursued as an effective formulation strategy for …

An increased number of amorphous formulations of poorly water soluble drugs are being
introduced into the market due to their higher transient solubility and thus faster absorption …

Co-amorphous drug delivery systems have recently gained considerable interest in the
pharmaceutical field because of their potential to improve oral bioavailability of poorly water …

The use of amorphous solid dispersions is an interesting strategy to increase the
bioavailability of poorly soluble drugs by improving their rate and extent of dissolution. Lack …

The maximum achievable concentration of a drug in solution is dictated by the chemical
potential of the solid form. Because an amorphous solid has a higher chemical potential …

The number of active pharmaceutical substances having high therapeutic potential but low
water solubility is constantly increasing, making it difficult to formulate these compounds as …

Amorphous solid dispersions are one of the most promising strategies to improve the oral
bioavailability of sparingly water-soluble drugs. Drug particle size reduction improved the …