Influenza A (H3N2) Antibody Responses to Standard-Dose Versus Enhanced Influenza Vaccine Immunogenicity in Older Adults and Prior Season's Vaccine Status

S Zhong, TWY Ng, DM Skowronski… - The Journal of …, 2024 - academic.oup.com
Background Annual influenza vaccination is recommended for older adults but repeated
vaccination with standard-dose influenza vaccine has been linked to reduced …

Standard-dose versus MF59-adjuvanted, high-dose or recombinant-hemagglutinin influenza vaccine immunogenicity in older adults: comparison of A (H3N2) …

S Zhong, TWY Ng, DM Skowronski… - The Journal of …, 2023 - europepmc.org
Background Annual influenza vaccination is recommended for older adults but repeated
vaccination with standard-dose influenza vaccine has been linked to reduced …

Comparative immunogenicity of several enhanced influenza vaccine options for older adults: a randomized, controlled trial

BJ Cowling, RAPM Perera… - Clinical Infectious …, 2020 - academic.oup.com
Background Enhanced influenza vaccines may improve protection for older adults, but
comparative immunogenicity data are limited. Our objective was to examine immune …

Immune responses to twice-annual influenza vaccination in older adults in Hong Kong

YH Tam, SA Valkenburg, RAPM Perera… - Clinical Infectious …, 2018 - academic.oup.com
Background Many health authorities recommend influenza vaccination of older adults to
reduce disease burden. We hypothesized that in tropical and subtropical areas with more …

Mid-season estimates of influenza vaccine effectiveness against influenza A (H3N2) hospitalization in the elderly in Quebec, Canada, January 2015

R Gilca, DM Skowronski, M Douville-Fradet, R Amini… - PLoS …, 2015 - journals.plos.org
Background The 2014/15 influenza season in Canada was characterized by an early
epidemic due to vaccine-mismatched influenza A (H3N2) viruses, disproportionately …

Impact of repeated yearly vaccination on immune responses to influenza vaccine in an elderly population

S Kitamura, M Matsushita, N Komatsu, Y Yagi… - American Journal of …, 2020 - Elsevier
Background The effectiveness of repeated vaccination for seasonal influenza remains
controversial. Here, we measured antibody responses to the influenza virus (A/H1N1 …

Factors associated with maintenance of antibody responses to influenza vaccine in older, community-dwelling adults

HK Talbot, LA Coleman, Y Zhu, S Spencer… - BMC infectious …, 2015 - Springer
Background Little is known about factors associated with maintenance of hemagglutinin
inhibition (HAI) antibodies after influenza vaccination in older adults. Methods Adults≥ 50 …

Moderate influenza vaccine effectiveness against influenza A (H1N1) pdm09 virus and low effectiveness against A (H3N2) virus among older adults during 2013 …

L Zhang, Y Pan, C Ma, W Duan, Y Sun… - Human Vaccines & …, 2018 - Taylor & Francis
Background: Since 2007, trivalent inactivated influenza vaccine has been provided free-of-
charge to older adults aged≥ 60 years in Beijing, China, but the data regarding influenza …

[HTML][HTML] Comparison of neutralizing antibody and cell-mediated immune responses to pandemic H1N1 2009 influenza virus before and after H1N1 2009 influenza …

JP Hsu, MC Phoon, GCH Koh, MIC Chen… - International Journal of …, 2012 - Elsevier
BACKGROUND: The recent H1N1 pandemic virus that emerged in 2009 resulted in high
morbidity rates mainly in younger individuals, albeit with relatively low mortality. We …

Immunogenicity of Enhanced Influenza Vaccines Against Mismatched Influenza Strains in Older Adults: A Review of Randomized Controlled Trials

J Youhanna, V Tran, R Hyer… - Influenza and Other …, 2024 - Wiley Online Library
Antigenic drift is a major driver of viral evolution and a primary reason why influenza
vaccines must be reformulated annually. Mismatch between vaccine and circulating viral …