Sterilising immunity that blocks infection for life, and thus prevents illness after infection, is
the ultimate goal for vaccines. Neither influenza infection nor vaccination provide sterilising …

The adaptive immune response to influenza virus infection is multifaceted and complex,
involving antibody and cellular responses at both systemic and mucosal levels. Immune …

Yearly vaccination against seasonal influenza viruses is recommended for certain
individuals at high risk of complications associated with influenza. It has been recommended …

Universal influenza virus vaccines: need for clinical trials | Nature Immunology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Influenza is a major respiratory pathogen causing annual outbreaks and occasional
pandemics. Influenza vaccination is the major method of prophylaxis. Currently annual …

Influenza virus infections remain a significant health burden worldwide, despite available
vaccines. Factors that contribute to this include a lack of broad coverage by current vaccines …

Zoonotic influenza viruses that are a few mutations away from pandemic viruses circulate in
animals, and can evolve into airborne-transmissible viruses in human beings. Paradoxically …

Influenza vaccines remain the most effective tools to prevent flu and its complications.
Trivalent or quadrivalent inactivated influenza vaccines primarily elicit antibodies towards …

Conflicting reports have emerged about the effectiveness of the live attenuated influenza
vaccine. The live attenuated influenza vaccine appears to protect particularly poorly against …

Highlights•Influenza infection is prevented by protective antibodies.•Flu-specific T cells can
reduce viral load and disease severity.•Stem region of HA and flu internal proteins (NP and …