AQP4-IgG is an autoantibody associated with neuromyelitis optica spectroscopic disorder
(NMOSD), a central nervous system inflammatory disease that requires early diagnosis and …

Background The discovery of a highly specific antibody against the aquaporin-4 (AQP4)
water channel (AQP4-IgG) unified the spectrum of neuromyelitis optica spectrum disorders …

A precise diagnosis for neuromyelitis optica spectrum disorders (NMOSD) is crucial to
improve patients' prognostic, which requires highly specific and sensitive tests. The cell …

Neuromyelitis Optica (NMO) is an autoimmune demyelinating disease, characterized by the
presence of autoantibody (NMO-IgG) to Aquaporin-4 (AQP4). NMO-IgG identification …

Anti-aquaporin-4 (AQP4) immunoglobulin G (IgG) is the core diagnostic biomarker for
neuromyelitis optica spectrum disorders (NMOSD). The cell-based assay (CBA) is a widely …

Neuromyelitis optica-immunoglobulin G (NMO-IgG) binds to aquaporin-4 (AQP4) water
channels in the central nervous system leading to immune-mediated injury. We have …

Neuromyelitis optica (NMO) is an autoimmune demyelinating disease characterized by the
presence of anti-aquaporin-4 (AQP4) antibodies in the patient sera. We recently reported …

Objective To determine whether distinct aquaporin-4 (AQP4)-IgG lineages play a role in
neuromyelitis optica spectrum disorder (NMOSD) pathogenesis, we profiled the AQP4-IgG …

Since the discovery of a specific autoantibody in patients with neuromyelitis optica spectrum
disorder (NMOSD) in 2004, the water channel aquaporin-4 (AQP4) has attracted attention as …

Serological markers of Nuromyelitis Optica (NMO), an autoimmune disorder of the central
nervous system, are autoantibodies targeting the astrocytic water channel aquaporin-4 …