Cytotoxicity and Antimycobacterial Properties of Pyrrolo[1,2-a]quinoline Derivatives: Molecular Target Identification and Molecular Docking Studies
KN Venugopala, V Uppar, S Chandrashekharappa… - Antibiotics, 2020 - mdpi.com
A series of ethyl 1-(substituted benzoyl)-5-methylpyrrolo [1, 2-a] quinoline-3-carboxylates 4a–
f and dimethyl 1-(substituted benzoyl)-5-methylpyrrolo [1, 2-a] quinoline-2, 3-dicarboxylates …
f and dimethyl 1-(substituted benzoyl)-5-methylpyrrolo [1, 2-a] quinoline-2, 3-dicarboxylates …
Antitubercular, cytotoxicity, and computational target validation of dihydroquinazolinone derivatives
A series of 2, 3-dihydroquinazolin-4 (1 H)-one derivatives (3a–3m) was screened for in vitro
whole-cell antitubercular activity against the tubercular strain H37Rv and multidrug-resistant …
whole-cell antitubercular activity against the tubercular strain H37Rv and multidrug-resistant …
Synthesis, antitubercular, antimicrobial activities and molecular docking study of quinoline bearing dihydropyrimidines
NC Desai, GM Kotadiya, KA Jadeja, KN Shah… - Bioorganic …, 2021 - Elsevier
In order to develop the antimicrobial and antitubercular agents, we have derived quinoline
bearing dihydropyrimidine analogues 5a-o and structures of these compounds were …
bearing dihydropyrimidine analogues 5a-o and structures of these compounds were …
Design, synthesis, biological evaluation and molecular modelling studies of novel quinoline derivatives against Mycobacterium tuberculosis
RS Upadhayaya, JK Vandavasi, NR Vasireddy… - Bioorganic & medicinal …, 2009 - Elsevier
We herein describe the synthesis and antimycobacterial activity of a series of 27 different
derivatives of 3-benzyl-6-bromo-2-methoxy-quinolines and amides of 2-[(6-bromo-2 …
derivatives of 3-benzyl-6-bromo-2-methoxy-quinolines and amides of 2-[(6-bromo-2 …
Synthesis, biological evaluation and molecular modelling insights of 2-arylquinazoline benzamide derivatives as anti-tubercular agents
New 2-arylquinazoline benzamide derivatives were synthesized and screened against
H37RV strain, compounds displayed specific and potent anti-mycobacterial activity against …
H37RV strain, compounds displayed specific and potent anti-mycobacterial activity against …
Synthesis, Characterization and Biological Evaluation of New 3,5-Disubstituted-Pyrazoline Derivatives as Potential Anti-Mycobacterium tuberculosis H37Ra …
A total of fourteen pyrazoline derivatives were synthesized through cyclo-condensation
reactions by chalcone derivatives with different types of semicarbazide. These compounds …
reactions by chalcone derivatives with different types of semicarbazide. These compounds …
Searching for new leads for tuberculosis: design, synthesis, and biological evaluation of novel 2-quinolin-4-yloxyacetamides
E Pitta, MK Rogacki, O Balabon, S Huss… - Journal of Medicinal …, 2016 - ACS Publications
In this study, a new series of more than 60 quinoline derivatives has been synthesized and
evaluated against Mycobacterium tuberculosis (H37Rv). Apart from the SAR exploration …
evaluated against Mycobacterium tuberculosis (H37Rv). Apart from the SAR exploration …
Synthesis and in vitro antitubercular activity of a series of quinoline derivatives
MVN De Souza, KC Pais, CR Kaiser, MA Peralta… - Bioorganic & medicinal …, 2009 - Elsevier
A series of 33 quinoline derivatives have been synthesized and evaluated for their in vitro
antibacterial activity against Mycobacterium tuberculosis H37Rv using the Alamar Blue …
antibacterial activity against Mycobacterium tuberculosis H37Rv using the Alamar Blue …
Synthesis and antitubercular evaluation of novel dibenzo [b, d] furan and 9-methyl-9H-carbazole derived hexahydro-2H-pyrano [3, 2-c] quinolines via Povarov reaction
A series of novel hexahydro-2H-pyrano [3, 2-c] quinoline analogues derived from dibenzo
[b, d] furan and 9-methyl-9H-carbazole has been synthesized in very good yields through …
[b, d] furan and 9-methyl-9H-carbazole has been synthesized in very good yields through …
Synthesis of new 7-chloro-4-phenoxyquinoline analogues as potential antitubercular agents
PS Salve, SG Alegaon - Medicinal Chemistry Research, 2018 - Springer
Molecular hybridization is a developing approach to design novel compounds by merger of
two or more biological subunits of known medicinal agents. In the present study, new series …
two or more biological subunits of known medicinal agents. In the present study, new series …