According to the free radical theory of aging, biological senescence processes develop from
a general failure to maintain organism's homeostasis, probably due to oxidative stress. The …

Oxidative stress has been implicated in the progression of ageing and in many age‐related
neurodegenerative conditions. Astrocytes play a major role in the antioxidant protection of …

Astrocytes are one of the predominant glial cell types in the adult central nervous system
functioning as both supportive and metabolic cells for the brain. Our objective in this …

The survival of neural tissues depends in part on the balance between the formation of free
radicals due to oxidative metabolism and the transformation of the free radicals to non-toxic …

Our data support a disproportion between free radicals levels and scavenging systems
activity in different cerebral regions of the aging rat. We investigated the total reactive …

Abstract The activities of Cu, Zn superoxide dismutase, glutathione peroxidase, catalase and
glutathione reductase in neuronal and glial cell-enriched fractions obtained from the …

The objective of this study was to determine the specific relationship between brain aging
and changes in the level of oxidative stress, lipid peroxidation (LPO) and in the activities of …

It has been proposed that neurodegenerative processes of aging are associated with the
generation of reactive oxygen species (ROS) during cellular metabolism. These reactive …

Objective To investigate whether two kinds of in vitro prepared advanced glycation end
products (AGEs), Glu-BSA and Gal-BSA, could change oxidation stress and anti-oxidation …

The aging brain undergoes a process of enhanced peroxidative stress, as shown by reports
of altered membrane lipids, oxidized proteins, and damaged DNA. The aims of this review …