A novel fluorescent ligand was synthesized as a high-affinity, high specificity probe for
visualizing the serotonin transporter (SERT). The rhodamine fluorophore was extended from …

Novel rhodamine-labeled ligands, based on (S)-citalopram, were synthesized and
evaluated for uptake inhibition at the human serotonin, dopamine, and norepinephrine …

Serotonin is a monoamine serving as a chemical messenger in diverse brain regions, as
well as in blood and various other organs. We synthesized six ethylamine functionalized …

To date, the development of photoaffinity ligands targeting the human serotonin transporter
(hSERT), a key protein involved in disease states such as depression and anxiety, have …

2β-Carbo (2-fluoroethoxy)-3β-(4 '-((Z)-2-iodoethenyl) phenyl) nortropane (βFE p ZIENT, 1)
was synthesized as a serotonin transporter (SERT) imaging agent for both positron emission …

The utilization of fluorescent ligands to study the monoamine transporters (MATs) has
increased our knowledge of their function and distribution in live cell systems. In this study …

The serotonin transporter (SERT) is the primary target for antidepressant drugs. The
existence of a high affinity primary orthosteric binding site (S1) and a low affinity secondary …

To establish a purification procedure for the human serotonin transporter (hSERT) we
expressed in Sf9 insect cells an epitope-tagged version of the transporter containing a FLAG …

Three serotonin reuptake inhibitors where the 5-cyano group in citalopram [1-(3-
dimethylamino-propyl)-1-(4-fluorophenyl)-1, 3-dihydroisobenzofuran-5-carbonitrile (1)] was …

Three photoaffinity ligands (PALs) for the human serotonin transporter (hSERT) were
synthesized based on the selective serotonin reuptake inhibitor (SSRI),(S)-citalopram (1) …