Targeting cellular cofactors in HIV therapy

R Dürr, O Keppler, F Christ, E Crespan… - Therapy of Viral …, 2015 - Springer
Besides viral proteins cellular factors play a key role in the replication of the human
immunodeficiency virus HIV-1. The outcome of virus replication is determined by the …

Cervical cancer-associated promoter polymorphism affects akna expression levels

GA Martínez-Nava, K Torres-Poveda… - Genes & …, 2015 - nature.com
Cervical cancer (CC) is responsible for> 260 000 deaths worldwide each year. Efforts are
being focused on identifying genetic susceptibility factors, especially in genes related to the …

B cells and antibodies in jawless vertebrates

BR Herrin, M Hirano, J Li, S Das, Y Sutoh… - Molecular biology of B …, 2015 - Elsevier
An adaptive immune system (AIS) based on clonally diverse lymphocytes that can recognize
specific pathogens and provide protective memory against a second encounter is found only …

Role of Cecr2 and Candidate Modifier Genes of Cecr2 in the Neural Tube Defect Exencephaly

RYM Leduc - 2015 - era.library.ualberta.ca
Neurulation, the early developmental process that forms the rudiment of the brain and spinal
cord, relies upon the intricate interplay of hundreds of genes in multiple genetic pathways …

[PDF][PDF] The Functional and Molecular Characterisation of the Novel DNA Damage Repair Protein Bod1L.

AM Davies - 2015 - discovery.dundee.ac.uk
DNA damage induces MDC1 recruitment and establishes a signalling platform that mediates
the DNA damage response (DDR). I show that Bod1L plays a central role in DDR by …

Homéostasie des histones en réponse au dommage à l'ADN et étude d'inhibiteurs de désacétylases d'importance clinique

V Villeneuve - 2015 - papyrus.bib.umontreal.ca
La chromatine possède une plasticité complexe et essentielle pour répondre à différents
mécanismes cellulaires fondamentaux tels la réplication, la transcription et la réparation de …

[PDF][PDF] Role of CTCF Poly (ADP-ribosyl) ation in the regulation of cellular functions

I Pavlaki - 2015 - repository.essex.ac.uk
ABSTRACT CTCF is an evolutionary conserved and ubiquitously expressed protein which
regulates a plethora of cellular functions using different molecular mechanisms. However …

Determining how Epstein-Barr Virus genomes are tethered to cellular chromosomes

A Chakravorty - 2015 - search.proquest.com
Epstein Barr virus (EBV) is a DNA tumour virus that is causally associated with several
human malignancies. EBV provides survival factors to its associated tumors; tumor cells that …

[图书][B] Xenogeneic Silencer MvaT Differs in its DNA Binding Mechanism from Family Members H-NS and Lsr2

G Tong - 2015 - search.proquest.com
Abstract Xenogeneic silencers (H-NS, Lsr2 and MvaT) facilitate bacterial evolution through
the cryptic maintenance of horizontally acquired genes, binding and transcriptionally …

[PDF][PDF] Molecular genetic analysis of two plant-specific gene families, SOFL and AHL, in Arabidopsis thaliana

R Tayengwa - 2015 - rex.libraries.wsu.edu
Previous studies revealed a small three-member SOFL gene family (SOB5, AtSOFL1 and
AtSOFL2) of unknown function involved in CK-mediated plant development. Transgenic …