We described a novel scandium-catalyzed selective Michael addition of quinazolinones and
vinylazaarenes. The protocol proceeds smoothly to give diverse quinazolinone derivatives …

Objective: A dimeric neolignan, bishonokiol A (BHNKA) isolated from Magnolia grandiflora,
significantly inhibits the proliferation of human breast cancer cells. However, the exact …

A series of 11 novel 3‐aryl‐2‐phenyl‐2, 3‐dihydro‐4 H‐1, 3‐benzothiazin‐4‐ones was
prepared at room temperature by T3P‐mediated cyclization of N‐aryl‐C‐phenyl imines with …

In this study, we scrutinized the anticancer effects of FB-15 on human gastric carcinoma
MGC-803 cells in vitro and vivo, and its preliminary effect on tubulin and HIF-1α. We …

The Ti (O-iPr) 4 and EtMgBr-catalyzed regio and stereoselective carbocyclization of N-allyl-
substituted 2-alkynylamines with Et2Zn, followed by deuterolysis or hydrolysis, affords the …

Natural products have been an inherent part of sustaining acculturation because of their
medicinal properties. Past discoveries of bioactive natural products have relied on …

Дисертація присвячена комплексному дослідженню нових трансформацій п'яти
гемінальних систем (OCN, NCN, OCO) в яких один із гетероатомів утворює лактамну …

In this study, a variety of new 1, 3-thiazin-4-one compounds bearing 1, 3, 4-thiadiazoles
and/or 1, 2, 4-triazoles moieties have been prepared via their relating Schiff bases with good …

The development and application of computer-aided drug design/discovery (CADD)
techniques (such as structured-base virtual screening, ligand-based virtual screening and …

Los compuestos sintetizados fueron evaluaron como agentes antiproliferativos contra un
panel representativo de cinco líneas celulares de tumores sólidos humanos y como agentes …