Evaluation of IGF-1 as a novel theranostic biomarker for schizophrenia

UH Yesilkaya, S Gica, MC Ilnem, M Sen… - Journal of Psychiatric …, 2021 - Elsevier
Objective In the current study, we aimed to investigate fasting plasma levels of glucose,
insulin, growth hormone, IGF-1, and lipid profile in remission schizophrenia patients …

[HTML][HTML] Association between serum insulin-like growth factor 1 levels and the clinical symptoms of chronic schizophrenia: preliminary findings

N Okamoto, K Yoshino, S Kitagawa, R Fujii… - Frontiers in …, 2021 - frontiersin.org
Purpose: Insulin-like growth factor 1 (IGF-1) is a trophic mediator that is regulated by growth
hormone and associated with the proliferation, development, and growth of neural cells. IGF …

Relationships between IGF-1, schizophrenia, and treatment of metabolic syndrome

A Demirel, OF Demirel, M Emül, A Duran… - Comprehensive psychiatry, 2014 - Elsevier
Objectives The use of atypical antipsychotic drugs in patients with psychiatric illness may
result in dyslipidemia, hypertension, glucose intolerance, and abdominal obesity, which are …

Elevated levels of Insulin-like Growth Factor-1 (IGF-1) in drug-naïve patients with psychosis

P Petrikis, VA Boumba, AT Tzallas, PV Voulgari… - Psychiatry …, 2016 - Elsevier
Insulin-like growth factor 1 (IGF-1) plays an important role in neurogenesis and
synaptogenesis and may be implicated in schizophrenia, although data so far have been …

Association between serum insulin-like growth factor 1 levels and the improvements of cognitive impairments in a subgroup of schizophrenia: Preliminary findings

J Xiong, Y Ding, X Wu, J Zhan, Q Wan, H Wan… - Schizophrenia …, 2024 - Elsevier
Background Numerous studies have implicated abnormal insulin-like growth factor 1 (IGF-1)
in the pathophysiology of schizophrenia, but findings have been inconsistent. Methods We …

[HTML][HTML] Altered insulin-like growth factor-2 signaling is associated with psychopathology and cognitive deficits in patients with schizophrenia

YJ Yang, T Luo, Y Zhao, SZ Jiang, JW Xiong, JQ Zhan… - PLoS …, 2020 - journals.plos.org
Background Schizophrenia is linked with abnormal brain neurodevelopment, on which IGF-
2 (insulin-like growth factor-2) has a great impact. The purpose of this study was to assess …

[HTML][HTML] Insulin-like growth factor 2 (IGF-2) and Insulin-like growth factor binding protein 7 (IGFBP-7) are upregulated after atypical antipsychotics in Spanish …

C Fernández-Pereira, MA Penedo… - International Journal of …, 2022 - mdpi.com
Insulin-like growth factor 2 (IGF-2) and IGF binding protein 7 (IGFBP-7) have been related to
schizophrenia (SZ) due to their implication in neurodevelopment. The purpose of this study …

The association between serum insulin-like growth factor 1 and cognitive impairments in patients with schizophrenia

X Chao, S Jiang, J Xiong, J Zhan, K Yan, Y Yang… - Psychiatry …, 2020 - Elsevier
Accumulating evidence has shown that insulin-like growth factors (IGFs) are implicated in
schizophrenia. Altered serum levels of IGF-1 have been found in schizophrenia patients and …

Effect of risperidone treatment on insulin-like growth factor-1 and interleukin-17 in drug naïve first-episode schizophrenia

D Chen, H Li, Q Zhao, J Song, C Lin, J Yu - Psychiatry Research, 2021 - Elsevier
Increasing evidence suggests that the inflammatory system is activated in schizophrenia and
antipsychotics may affect cytokines levels. we conducted a cross-sectional and prospective …

Relationship between negative symptoms and plasma levels of insulin-like growth factor 1 in first-episode schizophrenia and bipolar disorder patients

A Palomino, A González-Pinto… - Progress in Neuro …, 2013 - Elsevier
Previous studies have suggested that insulin-like growth factor-1 (IGF-1) is altered in
schizophrenia. The objective of this study was to investigate whether plasma IGF-1 levels …