Pharmacological agents under investigation in the treatment of coronavirus disease 2019 and the importance of melatonin

H Parlakpinar, S Polat, HA Acet - Fundamental & clinical …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a life‐threatening infectious respiratory
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …

[HTML][HTML] Therapeutic benefits of melatonin against COVID-19

M Mubashshir, N Ahmad, T Negi, R Rawal… - …, 2023 - karger.com
The assumption of the pineal hormone melatonin as a therapeutic use for COVID-19-
affected people seems promising. Its intake has shown significant improvement in the …

A mid‑pandemic night's dream: Melatonin, from harbinger of anti‑inflammation to mitochondrial savior in acute and long COVID‑19

IG Lempesis, VE Georgakopoulou… - International …, 2024 - spandidos-publications.com
Abstract Coronavirus disease 2019 (COVID‑19), a systemic illness caused by severe acute
respiratory distress syndrome 2 (SARS‑CoV‑2), has triggered a worldwide pandemic with …

[HTML][HTML] The coronavirus disease 2019 (COVID-19): key emphasis on melatonin safety and therapeutic efficacy

E Ramos, F Lopez-Munoz, E Gil-Martin, J Egea… - Antioxidants, 2021 - mdpi.com
Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The
current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore …

[HTML][HTML] Potential and possible therapeutic effects of melatonin on SARS-CoV-2 infection

E Shchetinin, V Baturin, E Arushanyan, A Bolatchiev… - Antioxidants, 2022 - mdpi.com
The absence of effective drugs for COVID-19 prevention and treatment requires the search
for new candidates among approved medicines. Fundamental studies and clinical …

[HTML][HTML] Pineal hormone melatonin as an adjuvant treatment for COVID‑19

M Vlachou, A Siamidi, A Dedeloudi… - International …, 2021 - spandidos-publications.com
The beneficial properties of the pineal hormone, melatonin, as a neuroprotective and
cardioprotective agent, have been previously identified. Furthermore, melatonin plays …

COVID-19: Melatonin as a potential adjuvant treatment

R Zhang, X Wang, L Ni, X Di, B Ma, S Niu, C Liu… - Life sciences, 2020 - Elsevier
This article summarizes the likely benefits of melatonin in the attenuation of COVID-19
based on its putative pathogenesis. The recent outbreak of COVID-19 has become a …

Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality

DX Tan, RJ Reiter - Life Sciences, 2022 - Elsevier
The fear of SARS-CoV-2 infection is due to its high mortality related to seasonal flu. To date,
few medicines have been developed to significantly reduce the mortality of the severe …

Can melatonin reduce the severity of COVID-19 pandemic?

A Shneider, A Kudriavtsev… - International reviews of …, 2020 - Taylor & Francis
The current COVID-19 pandemic is one of the most devastating events in recent history. The
virus causes relatively minor damage to young, healthy populations, imposing life …

[HTML][HTML] Therapeutic algorithm for use of melatonin in patients with COVID-19

RJ Reiter, P Abreu-Gonzalez, PE Marik… - Frontiers in …, 2020 - frontiersin.org
The coronavirus, COVID-19, has infected hundreds of thousands and killed tens of
thousands of individuals worldwide. This highly infectious condition continues to ravage the …