Neuropathic pain is chronic pain resulting from central or peripheral nerve damage that
remains difficult to treat. Current evidence suggests that nobiletin, isolated from Citrus …

Background: Inflammatory pain mediated by nuclear factor kappa-B (NF-κB) signal pathway
has become an increasingly important clinical issue in the last decade. As a potent …

Neuropathic pain is still a critical public health problem worldwide. Thereby, the search for
novel and more effective strategies against neuropathic pain is urgently considered. It is …

Chronic neuropathic pain poses a significant health problem worldwide, for which effective
treatment is lacking. The current work aimed to investigate the potential analgesic effect of …

Neuropathic pain arises from the injury of nervous system. The condition is extremely difficult
to be treated due to the ineffectiveness and presence of various adverse effects of the …

Neuropathic pain is often refractory to conventional pain therapies and thus requires
exploration of effective drugs. We evaluated if processed Aconiti tuber (PAT), a traditional …

Managing of neuropathic pain remains clinically challenging because the existing
pharmacotherapies are either ineffective or non-specific. Therefore, developing novel …

Background Due to the complications related to the use of the current pharmacological
approach for the alleviation of neuropathic pain, searching for effective compound with fewer …

Inflammatory pain and neuropathic pain are major health issues that represent considerable
social and economic burden worldwide. In this study we investigated the potential of …

Neuropathic pain is a major health issue that represents considerable social and economic
burden worldwidely. In this study, we investigated the potential of catalpol, an iridoid …