Endothelial to mesenchymal transition in health and disease

Y Xu, JC Kovacic - Annual Review of Physiology, 2023 - annualreviews.org
The endothelium is one of the largest organ systems in the body, and data continue to
emerge regarding the importance of endothelial cell (EC) dysfunction in vascular aging and …

Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review

JC Kovacic, S Dimmeler, RP Harvey, T Finkel… - Journal of the American …, 2019 - jacc.org
Endothelial to mesenchymal transition (EndMT) is a process whereby an endothelial cell
undergoes a series of molecular events that lead to a change in phenotype toward a …

Endothelial to mesenchymal transition: an insight in atherosclerosis

Q Huang, Y Gan, Z Yu, H Wu, Z Zhong - Frontiers in cardiovascular …, 2021 - frontiersin.org
Atherosclerosis is a fundamental disease of the cardiovascular system that leads to high
morbidity and mortality worldwide. The endothelium is the first protective barrier in …

Endothelial to mesenchymal transition in the cardiovascular system

H Gong, X Lyu, Q Wang, M Hu, X Zhang - Life Sciences, 2017 - Elsevier
Endothelial to mesenchymal transition (EndMT) is a special type of epithelial to
mesenchymal transition. It is a process that is characterized by the loss of features of …

Endothelial-to-mesenchymal transition: A novel therapeutic target for cardiovascular diseases

AO Jackson, J Zhang, Z Jiang, K Yin - Trends in Cardiovascular Medicine, 2017 - Elsevier
Endothelial-to-mesenchymal transition (EndMT) is a complex biological process in which
endothelial cells lose their specific markers and acquire a mesenchymal or myofibroblastic …

Endothelial-mesenchymal transition in cardiovascular disease

Z Alvandi, J Bischoff - Arteriosclerosis, thrombosis, and vascular …, 2021 - Am Heart Assoc
Endothelial-to-mesenchymal transition is a dynamic process in which endothelial cells
suppress constituent endothelial properties and take on mesenchymal cell behaviors. To …

Endothelial–mesenchymal transition in atherosclerosis

C Souilhol, MC Harmsen, PC Evans… - Cardiovascular …, 2018 - academic.oup.com
Atherosclerosis is an inflammatory disease resulting in the hardening and thickening of the
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …

Endothelial to mesenchymal transition represents a key link in the interaction between inflammation and endothelial dysfunction

JG Cho, A Lee, W Chang, MS Lee, J Kim - Frontiers in immunology, 2018 - frontiersin.org
Endothelial cells that line the inner walls of blood vessels are in direct contact with blood
and display remarkable heterogeneity in their response to exogenous stimuli. These ECs …

Endothelial-to-mesenchymal transition, vascular inflammation, and atherosclerosis

PY Chen, MA Schwartz, M Simons - Frontiers in cardiovascular …, 2020 - frontiersin.org
Atherosclerosis is a chronic progressive disease characterized by vascular inflammation
and growth of atherosclerotic plaque that eventually lead to compromise of blood flow. The …

Endothelial-to-mesenchymal transition: cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions

L Pérez, N Muñoz-Durango, CA Riedel… - Cytokine & growth factor …, 2017 - Elsevier
During the last decade, the endothelial-to-mesenchymal transition (EndMT) process has
attracted considerable attention due to associations with the onset of certain diseases, such …