Spatiotemporal Distribution and Function of Mitochondria in Oocytes

X Kang, L Yan, J Wang - Reproductive Sciences, 2024 - Springer
Mitochondria are energy provider organelles in eukaryotic cells that contain their own
specific genome. This review addresses structural and functional properties of mitochondria …

The role of mitochondrial dynamics in oocyte and early embryo development

RM Yildirim, E Seli - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Mitochondrial dysfunction is widely implicated in various human diseases, through
mechanisms that go beyond mitochondria's well-established role in energy generation …

[HTML][HTML] Mitochondria: Their relevance during oocyte ageing

J van der Reest, GN Cecchino, MC Haigis… - Ageing research …, 2021 - Elsevier
The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

Oocyte mitochondria—Key regulators of oocyte function and potential therapeutic targets for improving fertility

D Adhikari, I Lee, WS Yuen, J Carroll - Biology of Reproduction, 2022 - academic.oup.com
The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

Mitochondrial morphology, distribution and activity during oocyte development

D Bahety, E Böke, A Rodríguez-Nuevo - Trends in Endocrinology & …, 2024 - cell.com
Mitochondria have a crucial role in cellular function and exhibit remarkable plasticity,
adjusting both their structure and activity to meet the changing energy demands of a cell …

[HTML][HTML] Mitochondria in reproduction

MH Kang, YJ Kim, JH Lee - Clinical and Experimental …, 2023 - ncbi.nlm.nih.gov
In reproduction, mitochondria produce bioenergy, help to synthesize biomolecules, and
support the ovaries, oogenesis, and preimplantation embryos, thereby facilitating healthy …

Uncovering the important role of mitochondrial dynamics in oogenesis: impact on fertility and metabolic disorder transmission

MR Chiaratti - Biophysical Reviews, 2021 - Springer
Oocyte health is tightly tied to mitochondria given their role in energy production, metabolite
supply, calcium (Ca 2+) buffering, and cell death regulation, among others. In turn …

Mitochondria in early development: linking the microenvironment, metabolism and the epigenome

AJ Harvey - Reproduction, 2019 - rep.bioscientifica.com
Mitochondria, originally of bacterial origin, are highly dynamic organelles that have evolved
a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage …

[HTML][HTML] Mitochondria: the panacea to improve oocyte quality?

L Qi, X Chen, J Wang, B Lv, J Zhang… - Annals of Translational …, 2019 - ncbi.nlm.nih.gov
Oocyte quality is one of the most important factors involving in female reproduction. The
number of compromised oocytes will increase with maternal age, while mitochondrial …

The role of mitochondria in oocyte and early embryo health

K Kim, S Kenigsberg, A Jurisicova, Y Bentov - OBM Genetics, 2019 - lidsen.com
The mitochondria of the oocyte are a prominent source of energy metabolism as well as
mitochondrial DNA that will later populate the cells of the offspring. Recent discoveries …