Spatiotemporal constrained RNA–protein heterogeneous network for protein complex identification

Z Li, S Wang, H Cui, X Liu, Y Zhang - Briefings in Bioinformatics, 2024 - academic.oup.com
The identification of protein complexes from protein interaction networks is crucial in the
understanding of protein function, cellular processes and disease mechanisms. Existing …

Temporal Protein Complex Identification Based on Dynamic Heterogeneous Protein Information Network Representation Learning

Z Li, Y Zhang, P Zhou - IEEE/ACM Transactions on …, 2024 - ieeexplore.ieee.org
Protein complexes, as the fundamental units of cellular function and regulation, play a
crucial role in understanding the normal physiological functions of cells. Existing methods for …

Heterogeneous PPI network representation learning for protein complex identification

P Zhou, Y Zhang, F Chen, K Pang, M Lu - International Symposium on …, 2022 - Springer
Protein complexes are critical units for studying a cell system. How to accurately identify
protein complexes has always been the focus of research. Most of the existing methods are …

Protein Complex Identification Based on Heterogeneous Protein Information Network

P Zhou, Y Zhang, Z Li, K Pang… - Journal of Computational …, 2023 - liebertpub.com
Protein complexes are the foundation of all cellular activities, and accurately identifying them
is crucial for studying cellular systems. The efficient discovery of protein complexes is a …

PCGAN: a generative approach for protein complex identification from protein interaction networks

Y Pan, Y Wang, J Guan, S Zhou - Bioinformatics, 2023 - academic.oup.com
Motivation Protein complexes are groups of polypeptide chains linked by non-covalent
protein–protein interactions, which play important roles in biological systems and perform …

[HTML][HTML] An ensemble learning framework for detecting protein complexes from PPI networks

R Wang, H Ma, C Wang - Frontiers in Genetics, 2022 - frontiersin.org
Detecting protein complexes is one of the keys to understanding cellular organization and
processes principles. With high-throughput experiments and computing science …

COMNA: Core-attachment based protein complex detection via multiple network alignment

Y Chen, Y Zhu, M Zhong, J Liu - 2021 IEEE International …, 2021 - ieeexplore.ieee.org
Protein complexes are important functional units for performing biological functions and
revealing cellular organization principles, and its detection is a fundamental problem in …

DPCMNE: detecting protein complexes from protein-protein interaction networks via multi-level network embedding

X Meng, J Xiang, R Zheng, FX Wu… - IEEE/ACM Transactions …, 2021 - ieeexplore.ieee.org
Biological functions of a cell are typically carried out through protein complexes. The
detection of protein complexes is therefore of great significance for understanding the …

[HTML][HTML] Identifying protein complexes with clear module structure using pairwise constraints in protein interaction networks

G Liu, B Liu, A Li, X Wang, J Yu, X Zhou - Frontiers in Genetics, 2021 - frontiersin.org
The protein-protein interaction (PPI) networks can be regarded as powerful platforms to
elucidate the principle and mechanism of cellular organization. Uncovering protein …

Constructing a PPI Network Based on Deep Transfer Learning for Protein Complex Detection

X Yuan, H Deng, J Hu - IEEJ Transactions on Electrical and …, 2022 - Wiley Online Library
In the detection of protein complexes, the completeness of a protein–protein interaction (PPI)
network is crucial. Complete PPI networks, however, are not available for most species …