[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Bibliometric and visualized analysis of ocular drug delivery from 2001 to 2020

C Peng, L Kuang, J Zhao, AE Ross, Z Wang… - Journal of Controlled …, 2022 - Elsevier
Objective To perform a bibliometric analysis in the field of ocular drug delivery research to
characterize the current international trends and to present visual representations of the past …

The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

[HTML][HTML] Target specific tight junction modulators

J Brunner, S Ragupathy, G Borchard - Advanced drug delivery reviews, 2021 - Elsevier
Intercellular tight junctions represent a formidable barrier against paracellular drug
absorption at epithelia (eg, nasal, intestinal) and the endothelium (eg, blood–brain barrier) …

Smart contact lens systems for ocular drug delivery and therapy

TY Kim, GH Lee, J Mun, S Cheong, I Choi, H Kim… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular drug delivery and therapy systems have been extensively investigated with various
methods including direct injections, eye drops and contact lenses. Nowadays, smart contact …

[HTML][HTML] Drug delivery challenges and current progress in nanocarrier-based ocular therapeutic system

MH Akhter, I Ahmad, MY Alshahrani, AI Al-Harbi… - Gels, 2022 - mdpi.com
Drug instillation via a topical route is preferred since it is desirable and convenient due to the
noninvasive and easy drug access to different segments of the eye for the treatment of …

[HTML][HTML] Hydrogel biomaterials for application in ocular drug delivery

CR Lynch, PPD Kondiah, YE Choonara… - … in bioengineering and …, 2020 - frontiersin.org
There are many challenges involved in ocular drug delivery. These are a result of the many
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …

Drug delivery to the anterior segment of the eye: A review of current and future treatment strategies

M Mofidfar, B Abdi, S Ahadian, E Mostafavi… - International journal of …, 2021 - Elsevier
Research in the development of ophthalmic drug formulations and innovative technologies
over the past few decades has been directed at improving the penetration of medications …

Ocular drug delivery to the anterior segment using nanocarriers: A mucoadhesive/mucopenetrative perspective

RS Dave, TC Goostrey, M Ziolkowska… - Journal of Controlled …, 2021 - Elsevier
There is a growing demand for effective treatments for ocular conditions that improve patient
compliance and reduce side-effects. While methods such as implants and injections have …

[HTML][HTML] Microneedles for advanced ocular drug delivery

K Glover, D Mishra, S Gade, K Lalitkumar, Y Wu… - Advanced Drug Delivery …, 2023 - Elsevier
In the field of ocular drug delivery, topical delivery remains the most common treatment
option for managing anterior segment diseases, while intraocular injections are the current …