Interest in getting help to reduce or stop substance use among syringe exchange clients who use opioids
MC Frost, EC Williams, S Kingston… - Journal of addiction …, 2018 - journals.lww.com
Objectives: Opioid use is a growing problem in the United States. Despite existence of
effective treatments (eg, opioid agonist medication), most people with opioid use disorder do …
effective treatments (eg, opioid agonist medication), most people with opioid use disorder do …
Analysis of striatum and brain levels reveals sex differences in conversion of methamphetamine to amphetamine in mice
EJ Jaehne, JD Smith, M van den Buuse - Neuroscience Letters, 2022 - Elsevier
The aim of this study was to compare methamphetamine (Meth) and amphetamine (Amph)
levels in the brain of male and female mice. Meth and Amph levels were significantly higher …
levels in the brain of male and female mice. Meth and Amph levels were significantly higher …
Neuroprotective effect of histamine H3 receptor blockade on methamphetamine-induced cognitive impairment in mice
H Luo, X Li, R Fan, Y Ruan, L Qian, Y Shen, Z Si… - Pharmacology …, 2023 - Elsevier
Objective Methamphetamine (METH) exposure is commonly believed to result in cognitive
impairment. Histamine H3 receptor (H3R) antagonists reportedly have potential applications …
impairment. Histamine H3 receptor (H3R) antagonists reportedly have potential applications …
Riluzole for treatment of men with methamphetamine dependence: a randomized, double-blind, placebo-controlled clinical trial
MH Farahzadi, E Moazen-Zadeh… - Journal of …, 2019 - journals.sagepub.com
Background: Riluzole is a glutamate regulator and effective in treatment of neuropsychiatric
conditions. Aims: We assessed riluzole for treatment of methamphetamine dependence …
conditions. Aims: We assessed riluzole for treatment of methamphetamine dependence …
Investigational drug therapies in phase I and phase II clinical trials for alcohol use disorders
LC Walker, AJ Lawrence - Expert Opinion on Investigational Drugs, 2018 - Taylor & Francis
Introduction: Alcohol use disorder (AUD) is a complex psychiatric condition characterized by
craving, compulsive seeking, loss of control of alcohol consumption as well as the …
craving, compulsive seeking, loss of control of alcohol consumption as well as the …
Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway
B Shen, D Zhang, X Zeng, L Guan, G Yang, L Liu… - …, 2022 - Springer
Rationale Adaptive alteration of dopamine (DA) system in mesocorticolimbic circuits is an
extremely intricate and dynamic process, which contributes to maintaining …
extremely intricate and dynamic process, which contributes to maintaining …
Neurocognitive disorders in substance use disorders
Chronic use of different substances is associated with neural dysfunctions and related
cognitive deficits. Neurocognitive disorders encompass reward, negative affect and control …
cognitive deficits. Neurocognitive disorders encompass reward, negative affect and control …
Modafinil reduces amphetamine preference and prevents anxiety-like symptoms during drug withdrawal in young rats: Involvement of dopaminergic targets in VTA …
VT Dias, HZ Rosa, LF D'avila, LT Vey… - Progress in Neuro …, 2019 - Elsevier
Drug abuse and addiction are overwhelming health problems mainly during adolescence.
Based on a previous study of our research group, the rats that received modafinil (MD) …
Based on a previous study of our research group, the rats that received modafinil (MD) …
Chronic methamphetamine and psychosis pathways
Methamphetamine is a highly addictive psychostimulant with increasing global abuse
prevalence. The symptomatology of methamphetamine use includes a stimulant-induced …
prevalence. The symptomatology of methamphetamine use includes a stimulant-induced …
Trait impulsivity as a mediator between early cigarette smoking initiation and addiction severity in patients with methamphetamine use disorder
CY Huang, CC Hung, YJ Ho, SC Fang - International Journal of Mental …, 2024 - Springer
The prevalence of and mortality associated with methamphetamine use cause a concern. To
add insights regarding the mechanisms that drive the disease progression, we investigated …
add insights regarding the mechanisms that drive the disease progression, we investigated …