Objectives: Opioid use is a growing problem in the United States. Despite existence of
effective treatments (eg, opioid agonist medication), most people with opioid use disorder do …

The aim of this study was to compare methamphetamine (Meth) and amphetamine (Amph)
levels in the brain of male and female mice. Meth and Amph levels were significantly higher …

Objective Methamphetamine (METH) exposure is commonly believed to result in cognitive
impairment. Histamine H3 receptor (H3R) antagonists reportedly have potential applications …

Background: Riluzole is a glutamate regulator and effective in treatment of neuropsychiatric
conditions. Aims: We assessed riluzole for treatment of methamphetamine dependence …

Introduction: Alcohol use disorder (AUD) is a complex psychiatric condition characterized by
craving, compulsive seeking, loss of control of alcohol consumption as well as the …

Rationale Adaptive alteration of dopamine (DA) system in mesocorticolimbic circuits is an
extremely intricate and dynamic process, which contributes to maintaining …

Chronic use of different substances is associated with neural dysfunctions and related
cognitive deficits. Neurocognitive disorders encompass reward, negative affect and control …

Drug abuse and addiction are overwhelming health problems mainly during adolescence.
Based on a previous study of our research group, the rats that received modafinil (MD) …

Methamphetamine is a highly addictive psychostimulant with increasing global abuse
prevalence. The symptomatology of methamphetamine use includes a stimulant-induced …

The prevalence of and mortality associated with methamphetamine use cause a concern. To
add insights regarding the mechanisms that drive the disease progression, we investigated …