[HTML][HTML] COVID-19 complications: oxidative stress, inflammation, and mitochondrial and endothelial dysfunction

E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

[HTML][HTML] Hepatitis C virus and hepatocellular carcinoma: carcinogenesis in the era of direct-acting antivirals

F Fiehn, C Beisel, M Binder - Current Opinion in Virology, 2024 - Elsevier
Chronic hepatitis C virus (HCV) infection is a major cause of hepatic fibrosis and cirrhosis,
with a risk for the development of hepatocellular carcinoma (HCC). Although highly effective …

Multifaceted effects of subchronic exposure to chlorfenapyr in mice: implications from serum metabolomics, hepatic oxidative stress, and intestinal homeostasis

Y Xiong, X Ma, B He, J Zhi, X Liu, P Wang… - Journal of Agricultural …, 2024 - ACS Publications
As chlorfenapyr is a commonly used insecticide in agriculture, the health risks of subchronic
exposure to chlorfenapyr remained unclear. This study aimed to extensively probe the …

Climate warming has divergent physiological impacts on sympatric lizards

Z Ding, X Wang, T Zou, X Hao, Q Zhang, B Sun… - Science of The Total …, 2024 - Elsevier
Climate warming is expected to affect the vulnerability of sympatric species differentially due
to their divergent traits, but the underlying physiological mechanisms of those impacts are …

[HTML][HTML] MiRNAs in Alcohol-Related Liver Diseases and Hepatocellular Carcinoma: A Step toward New Therapeutic Approaches?

M Jouve, R Carpentier, S Kraiem, N Legrand… - Cancers, 2023 - mdpi.com
Simple Summary Alcohol-related Liver Disease (ALD) is the leading cause of chronic liver
disorders and the first cause of hepatocellular carcinoma in developed countries …

Organophosphate ester flame retardants and plasticizers affect the phenotype and function of HepG2 liver cells

D Yu, BF Hales, B Robaire - Toxicological Sciences, 2024 - academic.oup.com
Exposure to the organophosphate esters (OPEs), used as flame retardants and plasticizers,
is associated with a variety of adverse health effects including an increase in the incidence …

[HTML][HTML] Causal effect of porphyria biomarkers on alcohol-related hepatocellular carcinoma through Mendelian Randomization

X Yang, S Wang, C Sun, Y Xia - Plos one, 2024 - journals.plos.org
Purpose According to some cohort studies, an association exists between acute intermittent
porphyria (AIP) and liver cancer. However, establishing a definitive causal relationship …

Structure modification converts the hepatotoxic tacrine into novel hepatoprotective analogs

AA Sorour, RG Aly, HM Ragab, A Wahid - ACS omega, 2024 - ACS Publications
The liver is responsible for critical functions such as metabolism, secretion, storage,
detoxification, and the excretion of various compounds. However, there is currently no …

Melatonin mitigated methotrexate-induced hepatotoxicity through interrelated biological processes

N Abdallah, ME Amer, MA Amer, MA El-Missiry… - Molecular Biology …, 2024 - Springer
Background Hepatotoxicity associated with methotrexate (MTX) is mainly due to disruption
of redox balance and development of oxidative injury to hepatocytes. Melatonin (MLT) is a …

[HTML][HTML] Tannic acid-and N-acetylcysteine-chitosan-modified magnetic nanoparticles reduce hepatic oxidative stress in prediabetic rats

M Świętek, I Marková, H Malínská, M Hüttl… - Colloids and Surfaces B …, 2024 - Elsevier
Magnetic nanoparticles (MNPs) modified with tannic acid (TA) have shown remarkable
success as an antioxidant and antimicrobial therapeutic agent. Herein, we report a synthetic …