The potential role of miRNAs in the pathogenesis of testicular germ cell tumors-A Focus on signaling pathways interplay
Testicular germ cell tumors (TGCTs) are the most common testicular neoplasms in
adolescents and young males. Understanding the genetic basis of TGCTs represents a …
adolescents and young males. Understanding the genetic basis of TGCTs represents a …
miRNAs orchestration of testicular germ cell tumors–Particular emphasis on diagnosis, progression and drug resistance
Testicular cancer (TC) is one of the most frequently incident solid tumors in males. A growing
prevalence has been documented in developed countries. Although recent advances have …
prevalence has been documented in developed countries. Although recent advances have …
Recent insights into therapy resistance in osteosarcoma
ZD Prudowsky, JT Yustein - Cancers, 2020 - mdpi.com
Simple Summary Osteosarcoma is the most common cancer of the bone for children and
adolescents. Although chemotherapy regimens have been widely available and effective for …
adolescents. Although chemotherapy regimens have been widely available and effective for …
Utility of serum miR-371a-3p in predicting relapse on surveillance in patients with clinical stage I testicular germ cell cancer
J Lobo, R Leao, AJM Gillis, A van den Berg… - European Urology …, 2021 - Elsevier
Background Optimal management of clinical stage I (CSI) testicular cancer is controversial
due to lack of robust prognostic factors; miRNA-371a-3p holds promise as a biomarker …
due to lack of robust prognostic factors; miRNA-371a-3p holds promise as a biomarker …
The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors
V Miranda-Gonçalves, J Lobo… - Journal of Experimental …, 2021 - Springer
Abstract Background Germ cell tumors (GCTs) are developmental cancers, tightly linked to
embryogenesis and germ cell development. The recent and expanding field of RNA …
embryogenesis and germ cell development. The recent and expanding field of RNA …
Detection of recurrences using serum miR-371a-3p during active surveillance in men with stage I testicular germ cell tumours
CD Fankhauser, AJ Christiansen… - British journal of …, 2022 - nature.com
Abstract Background MiR-371a-3p predicts the presence of a macroscopic non-
teratomatous germ cell tumour (GCT). We hypothesised that miR-371a-3p can also detect …
teratomatous germ cell tumour (GCT). We hypothesised that miR-371a-3p can also detect …
Real-world application of pre-orchiectomy miR-371a-3p test in testicular germ cell tumor management
Purpose: Current serum tumor markers for testicular germ cell tumor are limited by low
sensitivity. Growing evidence supports the use of circulating miR-371a-3p as a superior …
sensitivity. Growing evidence supports the use of circulating miR-371a-3p as a superior …
Detection of recurrence through microRNA-371a-3p serum levels in a follow-up of stage I testicular germ cell tumors in the DRKS-00019223 study
G Belge, C Dumlupinar, T Nestler, M Klemke… - Clinical Cancer …, 2024 - AACR
Purpose: Surveillance of clinical stage I (CSI) testicular germ cell tumors (GCT) is hampered
by low sensitivity and specificity of current biomarkers for detecting relapses. This study …
by low sensitivity and specificity of current biomarkers for detecting relapses. This study …
MiRNA biomarkers in cancers of the male reproductive system: are we approaching clinical application?
V Constâncio, NT Tavares, R Henrique… - …, 2023 - Wiley Online Library
Background Specific cancer types face specific clinical management challenges. Owing to
their stability, robustness and fast, easy and cost‐effective detection, microRNAs (miRNAs) …
their stability, robustness and fast, easy and cost‐effective detection, microRNAs (miRNAs) …
Seminal plasma transcriptome and proteome: towards a molecular approach in the diagnosis of idiopathic male infertility
R Cannarella, F Barbagallo, A Crafa… - International journal of …, 2020 - mdpi.com
As the “-omic” technology has largely developed, its application in the field of medical
science seems a highly promising tool to clarify the etiology, at least in part, of the so-called …
science seems a highly promising tool to clarify the etiology, at least in part, of the so-called …