Renin-angiotensin system and sex differences in COVID-19: a critical assessment

MC Chappell - Circulation Research, 2023 - Am Heart Assoc
The current epidemic of corona virus disease (COVID-19) has resulted in an immense
health burden that became the third leading cause of death and potentially contributed to a …

Men, testosterone and Covid‐19

K Groti Antonic, B Antonic, M Caliber… - Clinical …, 2024 - Wiley Online Library
Men have more severe Coronavirus disease 2019 (Covid‐19) outcomes and higher
mortality rates than women, and it was suggested that testosterone levels might promote …

Divergent androgenic modulation of SARS-CoV-2 infection cooperates with dysregulated immune response to dictate worse COVID-19 outcomes in men

M Duarte-Silva, CNS Oliveira, C Fuzo… - Brain, behavior, and …, 2023 - Elsevier
Background Sex-determined differences are rarely addressed in the management of
diseases, despite well-known contrasting outcomes between female and male patients. In …

[HTML][HTML] Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database

EC Dos Reis, EL de Freitas Monteiro, J Meneguci… - BMC Public Health, 2023 - Springer
Previous studies have shown that associations between obesity and other comorbidities
favor worse outcomes in COVID-19. However, it is not clear how these factors interrelate and …

Sex hormones and the total testosterone: estradiol ratio as predictors of severe acute respiratory syndrome coronavirus 2 infection in hospitalized men

D Ruiz‐Ochoa, AR Guerra‐Ruiz… - …, 2024 - Wiley Online Library
Background The predictive ability of the early determination of sex steroids and the total
testosterone: estradiol ratio for the risk of severe coronavirus disease 2019 or the potential …

Integrating population-level and cell-based signatures for drug repositioning

C He, Y Xu, Y Zhou, J Fan, C Cheng, R Meng… - bioRxiv, 2023 - biorxiv.org
Drug repositioning presents a streamlined and cost-efficient way to expand the range of
therapeutic possibilities. Furthermore, drugs with genetic evidence are more likely to …

Serum Testosterone Is Associated With the Severity of COVID-19

E Suzuki, K Kuronuma, R Murai, Y Fujiya, A Saito… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: Coronavirus disease 2019 (COVID-19) is more likely to be severe in men
than in women. Its association with sex hormones as an aggravating factor for male patients …

Predicting Factors of Worse Prognosis in COVID-19: Results from a Cross-sectional Study on 52 Inpatients Admitted to the Internal Medicine Department

G Lisco, AG Solimando, A Stragapede… - Endocrine, metabolic & …, 2024 - iris.unitn.it
Background: The initial phases of the COVID-19 pandemic posed a real need for clinicians
to identify patients at risk of poor prognosis as soon as possible after hospital admission …

[HTML][HTML] Effects of SARS-CoV-2 and vaccination on male fertility–a review

M Freus, I Frulenko, A Kolasa - Pomeranian Journal of Life Sciences, 2023 - sciendo.com
The emergence of the second severe acute respiratory syndrome coronavirus (SARS-CoV-
2) has resulted in a global pandemic declared by the World Health Organization in 2020 …

Analiza serumske koncentracije citokina TWEAK i testosterona u bolesnika s teškim oblikom COVID-19

M Mikačić - 2024 - repozitorij.svkst.unist.hr
Uvod: Glavni patofiziološki mehanizam teškog oblika SARS-CoV-2 infekcije je poremećaj
imunološkog odgovora s razvojem citokinske oluje posredovane lučenjem brojnih …