[HTML][HTML] Metabolism of dietary and microbial vitamin B family in the regulation of host immunity

K Yoshii, K Hosomi, K Sawane, J Kunisawa - Frontiers in nutrition, 2019 - frontiersin.org
Vitamins are micronutrients that have physiological effects on various biological responses,
including host immunity. Therefore, vitamin deficiency leads to increased risk of developing …

Functional roles of B‐vitamins in the gut and gut microbiome

T Uebanso, T Shimohata, K Mawatari… - Molecular nutrition & …, 2020 - Wiley Online Library
The gut microbiota produce hundreds of bioactive compounds, including B‐vitamins, which
play significant physiological roles in hosts by supporting the fitness of symbiotic species …

Riboflavin transport and metabolism in humans

M Barile, TA Giancaspero, P Leone, M Galluccio… - Journal of inherited …, 2016 - Springer
Recent studies elucidated how riboflavin transporters and FAD forming enzymes work in
humans and create a coordinated flavin network ensuring the maintenance of cellular …

Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF-κB-mediated signaling

VS Subramanian, S Sabui… - American Journal …, 2018 - journals.physiology.org
Sodium-dependent vitamin C transporter-1 (SVCT-1) is the major transporter mediating
intestinal vitamin C uptake. Intestinal inflammation and prolonged infection are associated …

Medicinal Benefits, Biological and Nanoencapsulation Functions of Riboflavin with its Toxicity Profile-A Narrative Review

TY Lee, N Farah, VK Chin, CW Lim, PP Chong… - Nutrition Research, 2023 - Elsevier
Riboflavin is a precursor of the essential coenzymes flavin mononucleotide (FMN) and flavin
adenine dinucleotide (FAD). Both possess antioxidant properties and are involved in …

[PDF][PDF] Gastrointestinal handling of water-soluble vitamins

HM Said, E Nexo - Compr Physiol, 2018 - researchgate.net
Nine compounds are classified as water-soluble vitamins, eight B vitamins and one vitamin
C. The vitamins are mandatory for the function of numerous enzymes and lack of one or …

New insights into the neurodegeneration mechanisms underlying riboflavin transporter deficiency (RTD): involvement of energy dysmetabolism and cytoskeletal …

F Colasuonno, C Marioli, M Tartaglia, E Bertini… - Biomedicines, 2022 - mdpi.com
Riboflavin transporter deficiency (RTD) is a rare genetic disorder characterized by motor,
sensory and cranial neuropathy. This childhood-onset neurodegenerative disease is caused …

Development of novel experimental models to study flavoproteome alterations in human neuromuscular diseases: the effect of Rf therapy

M Tolomeo, A Nisco, P Leone, M Barile - International Journal of …, 2020 - mdpi.com
Inborn errors of Riboflavin (Rf) transport and metabolism have been recently related to
severe human neuromuscular disorders, as resulting in profound alteration of human …

Recent advances in riboflavin transporter RFVT and its genetic disease

C Jin, A Yonezawa - Pharmacology & Therapeutics, 2022 - Elsevier
Riboflavin (vitamin B2) is essential for cellular growth and function. It is enzymatically
converted to flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which …

Effect of the proinflammatory cytokine TNF-α on intestinal riboflavin uptake: inhibition mediated via transcriptional mechanism (s)

KY Anandam, OA Alwan… - … of Physiology-Cell …, 2018 - journals.physiology.org
Riboflavin (RF), is essential for normal cellular metabolism/function. Intestinal RF absorption
occurs via a specific carrier-mediated process that involves the apical transporter RFVT-3 …