Background: Pseudomonas aeruginosa (PA) is a Gram-negative pathogen responsible for
fatal nosocomial infections worldwide. Iron is essential for Gram-negative bacteria to …

Acinetobacter baumannii is an opportunistic pathogen that causes serious infections in
critically ill and immune compromised patients. The ability to acquire iron from the hosts iron …

Heme is an indispensable cofactor for almost all aerobic life, including the human host and
many bacterial pathogens. During infection, heme and hemoproteins are the largest source …

Heme is a versatile molecule that is vital for nearly all cellular life by serving as prosthetic
group for various enzymes or as nutritional iron source for diverse microbial species …

Pseudomonas aeruginosa is a priority pathogen for the development of new antibiotics,
particularly because multi-drug-resistant strains of this bacterium cause serious nosocomial …

Pseudomonas aeruginosa acquires extracellular heme via the Phu (Pseudomonas heme
uptake) and Has (heme assimilation system) systems. We have previously shown the …

Pseudomonas aeruginosa is an opportunistic pathogen that utilizes heme as a primary iron
source within the host. Extracellular heme is sensed via a heme assimilation system (has) …

Pseudomonas aeruginosa is an opportunistic pathogen requiring iron for its survival and
virulence. P. aeruginosa can acquire iron from heme via the nonredundant heme …

Chromobacterium violaceum is an environmental Gram-negative beta-proteobacterium that
causes systemic infections in humans. C. violaceum uses siderophore-based iron …

Iron is an essential nutrient for the survival and virulence of Pseudomonas aeruginosa. The
pathogen expresses at least 15 different iron‐uptake pathways, the majority involving small …