[HTML][HTML] Iron Acquisition Proteins of Pseudomonas aeruginosa as Potential Vaccine Targets: In Silico Analysis and In Vivo Evaluation of Protective Efficacy of the …
Background: Pseudomonas aeruginosa (PA) is a Gram-negative pathogen responsible for
fatal nosocomial infections worldwide. Iron is essential for Gram-negative bacteria to …
fatal nosocomial infections worldwide. Iron is essential for Gram-negative bacteria to …
Heme uptake and utilization by hypervirulent Acinetobacter baumannii LAC-4 is dependent on a canonical heme oxygenase (abHemO)
BJ Giardina, S Shahzad, W Huang, A Wilks - Archives of biochemistry and …, 2019 - Elsevier
Acinetobacter baumannii is an opportunistic pathogen that causes serious infections in
critically ill and immune compromised patients. The ability to acquire iron from the hosts iron …
critically ill and immune compromised patients. The ability to acquire iron from the hosts iron …
[HTML][HTML] The role of host heme in bacterial infection
RK Donegan - Biological Chemistry, 2022 - degruyter.com
Heme is an indispensable cofactor for almost all aerobic life, including the human host and
many bacterial pathogens. During infection, heme and hemoproteins are the largest source …
many bacterial pathogens. During infection, heme and hemoproteins are the largest source …
The diversity of heme sensor systems–heme-responsive transcriptional regulation mediated by transient heme protein interactions
A Krüger, M Keppel, V Sharma… - FEMS microbiology …, 2022 - academic.oup.com
Heme is a versatile molecule that is vital for nearly all cellular life by serving as prosthetic
group for various enzymes or as nutritional iron source for diverse microbial species …
group for various enzymes or as nutritional iron source for diverse microbial species …
[HTML][HTML] Targeted killing of Pseudomonas aeruginosa by pyocin G occurs via the hemin transporter Hur
I Atanaskovic, K Mosbahi, C Sharp, NG Housden… - Journal of molecular …, 2020 - Elsevier
Pseudomonas aeruginosa is a priority pathogen for the development of new antibiotics,
particularly because multi-drug-resistant strains of this bacterium cause serious nosocomial …
particularly because multi-drug-resistant strains of this bacterium cause serious nosocomial …
[HTML][HTML] Metabolite-driven regulation of heme uptake by the biliverdin IXβ/δ-selective heme oxygenase (HemO) of Pseudomonas aeruginosa
S Mouriño, BJ Giardina, H Reyes-Caballero… - Journal of Biological …, 2016 - ASBMB
Pseudomonas aeruginosa acquires extracellular heme via the Phu (Pseudomonas heme
uptake) and Has (heme assimilation system) systems. We have previously shown the …
uptake) and Has (heme assimilation system) systems. We have previously shown the …
[HTML][HTML] Post-transcriptional regulation of the Pseudomonas aeruginosa heme assimilation system (Has) fine-tunes extracellular heme sensing
AT Dent, S Mouriño, W Huang, A Wilks - Journal of Biological Chemistry, 2019 - ASBMB
Pseudomonas aeruginosa is an opportunistic pathogen that utilizes heme as a primary iron
source within the host. Extracellular heme is sensed via a heme assimilation system (has) …
source within the host. Extracellular heme is sensed via a heme assimilation system (has) …
[HTML][HTML] The heme-binding protein PhuS transcriptionally regulates the Pseudomonas aeruginosa tandem sRNA prrF1, F2 locus
T Wilson, S Mouriño, A Wilks - Journal of Biological Chemistry, 2021 - ASBMB
Pseudomonas aeruginosa is an opportunistic pathogen requiring iron for its survival and
virulence. P. aeruginosa can acquire iron from heme via the nonredundant heme …
virulence. P. aeruginosa can acquire iron from heme via the nonredundant heme …
[HTML][HTML] The Regulatory Protein ChuP Connects Heme and Siderophore-Mediated Iron Acquisition Systems Required for Chromobacterium violaceum Virulence
VM de Lima, BB Batista… - Frontiers in Cellular and …, 2022 - frontiersin.org
Chromobacterium violaceum is an environmental Gram-negative beta-proteobacterium that
causes systemic infections in humans. C. violaceum uses siderophore-based iron …
causes systemic infections in humans. C. violaceum uses siderophore-based iron …
Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA
V Will, V Gasser, L Kuhn, S Fritsch, DE Heinrichs… - FEBS …, 2023 - Wiley Online Library
Iron is an essential nutrient for the survival and virulence of Pseudomonas aeruginosa. The
pathogen expresses at least 15 different iron‐uptake pathways, the majority involving small …
pathogen expresses at least 15 different iron‐uptake pathways, the majority involving small …