Metastasis is a major cause of morbidity and mortality in cancer patients. However, the
molecular and cellular mechanisms underlying the ability of cancer cells to metastasize …

The pleural space, a sterile secluded environment in the thoracic cavity, represents an
attractive metastatic site for various cancers of lung, breast and gastrointestinal origins …

Background The approach to palliative treatment of malignant pleural effusion (MPE) should
be individualized because these patients generally have poor survival. Our study aimed to …

Malignant pleural effusion (MPE) is an indication of advanced cancer. Immune dysfunction
often occurs in MPE. We aimed to identify the reason for impaired T cell activity in MPE from …

Background: The survival of patients with malignant pleural effusion is considered generally
poor. Most of the studies reporting results of prognostic factors are retrospective, using …

Summary Background/Purpose Malignant pleural effusion is a frequent situation in
pulmonary medicine. However, it is sometimes difficult to recognize the underlying etiology …

Purpose Malignant pleural effusions (MPEs) are often observed in lung cancer, particularly
adenocarcinoma. The aim of this study was to investigate epidermal growth factor receptor …

Background Vascular endothelial growth factor (VEGF) is a critical regulator of malignant
pleural effusion (MPE) in non-small-cell lung cancer (NSCLC). Bevacizumab (BEV) and …

Background The use tumor-derived cell-free DNA extracted from body fluids is being
evaluated for genetic testing in lung cancer. The aim of this study was to explore the …

Background and objective LENT and PROMISE scores prognosticate survival in patients
with MPE. Prognostication guides the selection of interventions and management. However …