Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …

Cell death is critical for the development and homeostasis of almost all multicellular
organisms. Moreover, its dysregulation leads to diverse disease states. Historically …

The NLRP3 inflammasome is a cytosolic multiprotein complex composed of the innate
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …

Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

In recent decades, chemotherapies targeting apoptosis have emerged and demonstrated
remarkable achievements. However, emerging evidence has shown that chemoresistance is …

Ovarian cancer (OC) is a highly malignant gynaecological tumour that has a very poor
prognosis. Pyroptosis has been demonstrated in recent years to be an inflammatory form of …

Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …

Cytokine Storm Cytokine storm, a life-threatening disorder involving cytokine elevations and
immune-cell hyperactivation, has various causes and is characterized by constitutional …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …