New insights on COX-2 in chronic inflammation driving breast cancer growth and metastasis

HJ Hugo, C Saunders, RG Ramsay… - Journal of mammary …, 2015 - Springer
The medicinal use of aspirin stretches back to ancient times, before it was manufactured in
its pure form in the late 19th century. Its accepted mechanistic target, cyclooxygenase (COX) …

Cox-2 in non-small cell lung cancer: a meta-analysis

H Jiang, J Wang, W Zhao - Clinica chimica acta, 2013 - Elsevier
BACKGROUND: We investigated the prognostic value of cyclooxygenase-2 (COX-2) for
survival of patients with non-small cell lung cancer (NSCLC). METHODS: We performed a …

Combined analysis of vascular endothelial growth factor expression with cyclooxygenase-2 and mast cell density in oral squamous cell carcinoma

A Akbarzadeh Baghban, N Taghavi, M Shahla - Pathobiology, 2017 - karger.com
Background: Overexpression of vascular endothelial growth factor (VEGF) and
cyclooxygenase-2 (COX-2) and increasing mast cell density (MCD) in premalignant and …

Impact and mechanism of non-steroidal anti-inflammatory drugs combined with chemotherapeutic drugs on human lung cancer-nude mouse transplanted tumors

W Sun, G Chen - Oncology Letters, 2016 - spandidos-publications.com
The present study aimed to investigate the impact of indomethacin treatment combined with
oxaliplatin treatment on the expression of cluster of differentiation 44 variant 6 (CD44v6) …

[HTML][HTML] Celecoxib attenuates cachectic events in mice by modulating the expression of vascular endothelial growth factor

X Xu, M Jiang, Y Zhang, Y Bi… - Molecular Medicine …, 2015 - spandidos-publications.com
Chronic inflammation is one of the main symptoms of cancer cachexia, and cyclooxygenase
2 inhibitors, such as celecoxib, may be beneficial in counteracting the major symptoms of …

[HTML][HTML] Immunohistochemical expression of nuclear factor kappa-B/p65 and cyclooxygenase-2 in non-small cell lung cancer patients: Prognostic value and impact on …

GHA El-Magd, O Abd El-Fattah, EM Saied - Egyptian Journal of Chest …, 2014 - Elsevier
Introduction Nuclear factor kappa B/p65 (NF-κB/p65) regulates the expression of various
molecules important in tumorigenesis as cyclooxygenase-2 (COX-2). Aim To study the …

Differential expression of cyclooxygenase-2 and cyclin D1 in salivary gland tumors

JR Tenório, LP da Silva, MGA Xavier, T Santana… - European Archives of …, 2018 - Springer
Purpose Salivary gland tumors are complex and have a great histomorphological diversity;
more than 30 histological subtypes are currently described and the study of proteins that …

Lack of Association of the Cyclooxygenase-2 Gene 8473T> C Polymorphism with Breast Cancer Risk: a Meta-analysis

X Yang, F Zhao, YH Li, M Huang… - Asian Pacific Journal of …, 2014 - koreascience.kr
Background: Associations between the 8473T> C polymorphism (rs5275) in the
cyclooxygenase-2 (COX-2) gene and breast cancer (BC) risk are still inconclusive and …

Avaliação da Expressão da COX-2 em Tumores Mamários de Cadela

DCS Marques - 2013 - search.proquest.com
Abstract A ciclooxigenase-2 (COX-2) é uma proteína que se encontra envolvida na
oncogénese e na inflamação, tendo sido demonstrada a sua sobrexpressão em diversas …

[引用][C] COX-2, TTF-1 及p63 蛋白在非小细胞肺癌中的表达及临床意义

刘江, 胡静, 任伟, 谢丽, 史炯, 孟凡青, 刘宝瑞… - 现代肿瘤医学, 2015