Cancer is one of the highest prevalent diseases in humans. The chances of surviving cancer
and its prognosis are very dependent on the affected tissue, body location, and stage at …

Substantial evidence supports a functional role for cyclooxygenase‐and lipoxygenase‐
catalyzed arachidonic and linoleic acid metabolism in cancer development. Genetic …

Background Although lung cancer is among the few malignancies for which we know the
primary etiological agent (ie, cigarette smoke), a precise understanding of the temporal …

Background COX-2 is overexpressed in some cancers, including prostate cancer; however,
little is known about the effect of COX-2 overexpression on outcome in radiation-treated …

Many tumors, including Hodgkin's lymphoma, are associated with decreased cellular
immunity and elevated levels of prostaglandin E2 (PGE2), a known inhibitor of CD4+ T cell …

The biological role of COX-2, the inducible form of cyclooxygenase, is to convert arachidonic
acid into prostaglandins (PGs) and thromboxanes (TXs). Overexpressed in many tumors …

Objective The present study aimed to evaluate the anti-inflammatory and analgesic activities
of the ginsenoside metabolite compound K (CK) and its mechanisms. Methods Mice model …

Lung cancer risk was investigated in relation to single nucleotide polymorphisms in genes
involved in the inflammatory response. The aim was to see if polymorphisms modifying the …

Previous studies demonstrated that a subpopulation of cancer cells, which are CD133
positive (CD133+) feature higher invasive and metastatic abilities, are called cancer stem …

Objectives: Preclinical observations that selective cyclooxygenase-2 inhibitors enhance in
vitro cell radiosensitivity and in vivo tumor radioresponse led to clinical trials testing …