Cancer is one of the most common causes of death. So, its lethal effect increases with time.
Near about hundreds of cancers are known in humans. Cancer treatment is done to cure or …

Vision impairment has devastating consequences for the quality of human life. The cells and
tissues associated with the visual process must function throughout one's life span and …

Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs), which are pivotal sensors of
RNA virus invasions, mediate the transcriptional induction of genes encoding type I …

Stimulator of interferon genes (STING) is a key mediator of type-I interferon (IFN-I) signaling
in response to a variety of stimuli, but the contribution of STING to homeostatic processes is …

Kidney cancer is one of the most common urological cancers worldwide, and kidney renal
clear cell cancer (KIRC) is the major histologic subtype. Our previous study found that von …

The protein ISG15 encoded by interferon-stimulated gene (ISG) 15 is the first identified
member of the ubiquitin-like protein family and exists in the form of monomers and …

Beclin-1 is the firstly-identified mammalian protein of the autophagy machinery, which
functions as a molecular scaffold for the assembly of PI3KC3 (class III phosphatidylinositol 3 …

Ubiquitin-like proteins (Ubls) share some features with ubiquitin (Ub) such as their globular
3D structure and the ability to attach covalently to other proteins. Interferon Stimulated Gene …

Acute kidney injury (AKI) is a life-threatening health condition associated with increasing
morbidity and mortality. Despite extensive research on the mechanisms underlying AKI …

Immune regulation plays a crucial role in human health and disease. Inflammatory bowel
disease (IBD) is a chronic relapse bowel disease with an increasing incidence worldwide …