[HTML][HTML] Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer …
Z Yu, W Guo, X Ma, B Zhang, P Dong, L Huang… - Molecular cancer, 2014 - Springer
Abstract Background Gamabufotalin (CS-6), a major bufadienolide of Chansu, has been
used for cancer therapy due to its desirable metabolic stability and less adverse effect …
used for cancer therapy due to its desirable metabolic stability and less adverse effect …
HER2 induces cell proliferation and invasion of non-small-cell lung cancer by upregulating COX-2 expression via MEK/ERK signaling pathway
F Chi, R Wu, X Jin, M Jiang, X Zhu - OncoTargets and therapy, 2016 - Taylor & Francis
HER2 positivity has been well studied in various cancers, but its importance in non-small-
cell lung cancer (NSCLC) is still being explored. In this study, quantitative reverse …
cell lung cancer (NSCLC) is still being explored. In this study, quantitative reverse …
[HTML][HTML] Systematic evaluation of genetic variants in three biological pathways on patient survival in low-stage non-small cell lung cancer
Introduction Studies from selected candidate genes suggest that single-nucleotide
polymorphisms (SNPs) involved in glutathione metabolism, DNA repair, or inflammatory …
polymorphisms (SNPs) involved in glutathione metabolism, DNA repair, or inflammatory …
Histamine regulates cyclooxygenase 2 gene activation through Orai1-mediated NFκB activation in lung cancer cells
Histamine, an important chemical mediator, has been shown to regulate inflammation and
allergic responses. Stimulation of histamine receptors results in a significant increase in …
allergic responses. Stimulation of histamine receptors results in a significant increase in …
[HTML][HTML] Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer
H Luo, Z Chen, H Jin, M Zhuang, T Wang, C Su… - Journal of experimental …, 2011 - Springer
Background Vascular endothelial growth factor (VEGF) expression is up-regulated via a
cyclooxygenase-2 (COX-2)-dependent mechanism in non-small cell lung cancer (NSCLC) …
cyclooxygenase-2 (COX-2)-dependent mechanism in non-small cell lung cancer (NSCLC) …
Association of the −14C/G MET and the −765G/C COX-2 Gene Polymorphisms with the Risk of Chronic Rhinosinusitis with Nasal Polyps in a Polish Population
P Sitarek, H Zielinska-Blizniewska, L Dziki… - DNA and cell …, 2012 - liebertpub.com
Chronic rhinosinusitis with nasal polyps is strongly associated with other diseases, including
asthma and allergy. The following study tested the association of the− 765G/C …
asthma and allergy. The following study tested the association of the− 765G/C …
[HTML][HTML] Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer
W Li, W Yue, H Wang, B Lai, X Yang… - Oncology …, 2016 - spandidos-publications.com
The objective of the present study was to investigate whether cyclooxygenase-2 (COX-2) is
associated with malignancy, and to investigate its molecular mechanisms in human lung …
associated with malignancy, and to investigate its molecular mechanisms in human lung …
Genetic variants in MMP9 and TCF2 contribute to susceptibility to lung cancer
J Sun, X Yang, N Hu, X Li, F Li, M Li - Chinese Journal of Cancer …, 2011 - Springer
Abstract Objective| The Wnt signaling pathway is crucial for pulmonary development and
differentiation; dysregulation of the Wnt signaling pathway may impair lung function. Indeed …
differentiation; dysregulation of the Wnt signaling pathway may impair lung function. Indeed …
[HTML][HTML] Association of CHEK2 polymorphisms with the efficacy of platinum-based chemotherapy for advanced non-small-cell lung cancer in Chinese never-smoking …
W Xu, D Liu, Y Yang, X Ding, Y Sun… - Journal of Thoracic …, 2016 - ncbi.nlm.nih.gov
Background Cell cycle checkpoint kinase 2 (CHEK2) plays an essential role in the repair of
DNA damage. Single nucleotide polymorphisms (SNPs) in DNA repair genes are thought to …
DNA damage. Single nucleotide polymorphisms (SNPs) in DNA repair genes are thought to …
褪黑素增强紫杉醇对膀胱癌T24 细胞增殖的抑制作用.
陈欢， 朱佳斌， 赵晓瑾， 董传江… - Tianjin Medical …, 2020 - search.ebscohost.com
目的观察褪黑素(melatonin, Mel) 与紫杉醇(paclitaxel, PTX) 协同对膀胱癌T24 细胞的抑制作用,
并探讨其作用机制. 方法Mel 和化疗药物PTX 单独使用或者联合使用处理T24 细胞, 用CCK-8 …
并探讨其作用机制. 方法Mel 和化疗药物PTX 单独使用或者联合使用处理T24 细胞, 用CCK-8 …