Cannabidiol-loaded nanocarriers and their therapeutic applications

E Assadpour, A Rezaei, SS Das, BV Krishna Rao… - Pharmaceuticals, 2023 - mdpi.com
Cannabidiol (CBD), one of the most promising constituents isolated from Cannabis sativa,
exhibits diverse pharmacological actions. However, the applications of CBD are restricted …

Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow

WM Shaw, Y Zhang, X Lu, AS Khalil, G Ladds… - Nature …, 2022 - nature.com
Microbial production of cannabinoids promises to provide a consistent, cheaper, and more
sustainable supply of these important therapeutic molecules. However, scaling production to …

Cannabinoid therapy in epilepsy

S Billakota, O Devinsky, E Marsh - Current opinion in neurology, 2019 - journals.lww.com
Summary Identification of CBD, Δ9-THC, and the endocannabinoid system in the mid-20th
century has led to advancement of cannabis-based therapies for epilepsy. Based on clinical …

The endocannabinoid system and oligodendrocytes in health and disease

AA Ilyasov, CE Milligan, EP Pharr… - Frontiers in …, 2018 - frontiersin.org
Cannabinoid-based interventions are being explored for central nervous system (CNS)
pathologies such as neurodegeneration, demyelination, epilepsy, stroke, and trauma. As …

[HTML][HTML] Maternal marijuana use has independent effects on risk for spontaneous preterm birth but not other common late pregnancy complications

SY Leemaqz, GA Dekker, LM McCowan… - Reproductive …, 2016 - Elsevier
Widespread legalisation of marijuana raises safety concerns for its use in pregnancy. This
study investigated the association of marijuana use prior to and during pregnancy with …

Cannabidiol and epilepsy: Rationale and therapeutic potential

A Leo, E Russo, M Elia - Pharmacological research, 2016 - Elsevier
Despite the introduction of new antiepileptic drugs (AEDs), the quality of life and therapeutic
response for patients with epilepsy remains still poor. Unfortunately, besides several …

Natural product-derived therapies for treating drug-resistant epilepsies: from ethnopharmacology to evidence-based medicine

S Challal, A Skiba, M Langlois, CV Esguerra… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Epilepsy is one of the most prevalent neurological human
diseases, affecting 1% of the population in all age groups. Despite the availability of over 25 …

Cannabinoids in pediatrics

CT Campbell, MS Phillips… - The Journal of Pediatric …, 2017 - meridian.allenpress.com
Despite its controversial nature, the use of medical marijuana and cannabis-derived
medicinal products grows more popular with each passing year. As of November 2016, over …

Cannabinoid treatments in epilepsy and seizure disorders

O Devinsky, NA Jones, MO Cunningham… - Physiological …, 2024 - journals.physiology.org
Cannabis has been used to treat convulsions and other disorders since ancient times. In the
last few decades, preclinical animal studies and clinical investigations have established the …

The effects of cannabinoids on the endocrine system

M Borowska, A Czarnywojtek… - Endokrynologia …, 2018 - journals.viamedica.pl
Cannabinoids are the derivatives of the cannabis plant, the most potent bioactive
component of which is tetrahydrocannabinol (THC). The most commonly used drugs …