Epilepsy: key experimental therapeutics in early clinical development
C Steriade, J French, O Devinsky - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Antiseizure medications are the mainstay of epilepsy treatment. Currently
therapies are not specific to epilepsy etiology, and control seizures in two-thirds of cases …
therapies are not specific to epilepsy etiology, and control seizures in two-thirds of cases …
Cannabidiol and neurodevelopmental disorders in children
KA Kwan Cheung, MD Mitchell, HS Heussler - Frontiers in Psychiatry, 2021 - frontiersin.org
Neurodevelopmental and neuropsychiatric disorders (such as autism spectrum disorder)
have broad health implications for children, with no definitive cure for the vast majority of …
have broad health implications for children, with no definitive cure for the vast majority of …
Transporter Hypothesis in Pharmacoresistant Epilepsies: Is it at the Central or Peripheral Level?
L Czornyj, J Auzmendi, A Lazarowski - Pharmacoresistance in Epilepsy …, 2023 - Springer
The multidrug resistance (MDR) phenotype characterizes patients with refractory epilepsy
(RE). Seizures are not controlled despite receiving various combinations of more than two …
(RE). Seizures are not controlled despite receiving various combinations of more than two …
Attitudes toward legalization of marijuana in the United States, 1986-2016: Changes in determinants of public opinion
BE Denham - International Journal of Drug Policy, 2019 - Elsevier
Background Based on recent research in political science, which has conceptualized
political party affiliation as a form of social identity, the present study examined political …
political party affiliation as a form of social identity, the present study examined political …
Drug–drug interactions with cannabidiol (CBD) appear to have no effect on treatment response in an open-label Expanded Access Program
TE Gaston, EM Bebin, GR Cutter, SB Ampah, Y Liu… - Epilepsy & behavior, 2019 - Elsevier
Objective We have previously shown that cannabidiol (CBD; Epidiolex®) significantly affects
levels of clobazam/N-desmethylclobazam, rufinamide, topiramate, zonisamide, and …
levels of clobazam/N-desmethylclobazam, rufinamide, topiramate, zonisamide, and …
Duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients
L Treat, KE Chapman, KL Colborn, KG Knupp - Epilepsia, 2017 - Wiley Online Library
Objective Oral cannabis extracts (OCE s) are being used in the treatment of epilepsy with
increasing rates in the United States following product legalization; however, no studies …
increasing rates in the United States following product legalization; however, no studies …
Recent advances in status epilepticus
Recent advances in status epilepticus : Current Opinion in Neurology Recent advances in
status epilepticus : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …
status epilepticus : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …
Cognitive and behavioral effects of cannabidiol in patients with treatment-resistant epilepsy
B Metternich, K Wagner, MJ Geiger, M Hirsch… - Epilepsy & Behavior, 2021 - Elsevier
Purpose Therapeutic use of cannabidiol (CBD) in intractable epilepsies has increased
considerably over the last ten years. As more evidence for the potentially beneficial effects of …
considerably over the last ten years. As more evidence for the potentially beneficial effects of …
Development of a new method for the analysis of cannabinoids in honey by means of high-performance liquid chromatography coupled with electrospray ionisation …
V Brighenti, M Licata, T Pedrazzi, D Maran… - … of Chromatography A, 2019 - Elsevier
Fibre-type Cannabis sativa L.(hemp) represents a valuable resource in many different fields,
including both the pharmaceutical and food ones. This plant contains non-psychoactive …
including both the pharmaceutical and food ones. This plant contains non-psychoactive …
A conversion of oral cannabidiol to delta9-tetrahydrocannabinol seems not to occur in humans
G Nahler, F Grotenhermen, AW Zuardi… - Cannabis and …, 2017 - liebertpub.com
Cannabidiol (CBD), a major cannabinoid of hemp, does not bind to CB1 receptors and is
therefore devoid of psychotomimetic properties. Under acidic conditions, CBD can be …
therefore devoid of psychotomimetic properties. Under acidic conditions, CBD can be …