Coronary calcium score and cardiovascular risk

P Greenland, MJ Blaha, MJ Budoff, R Erbel… - Journal of the American …, 2018 - jacc.org
Coronary artery calcium (CAC) is a highly specific feature of coronary atherosclerosis. On
the basis of single-center and multicenter clinical and population-based studies with short …

Biological Versus Chronological Aging: JACC Focus Seminar

MR Hamczyk, RM Nevado, A Barettino, V Fuster… - Journal of the American …, 2020 - jacc.org
Aging is the main risk factor for vascular disease and ensuing cardiovascular and
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …

Low-attenuation noncalcified plaque on coronary computed tomography angiography predicts myocardial infarction: results from the multicenter SCOT-HEART trial …

MC Williams, J Kwiecinski, M Doris, P McElhinney… - Circulation, 2020 - Am Heart Assoc
Background: The future risk of myocardial infarction is commonly assessed using
cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis …

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

AL Durham, MY Speer, M Scatena… - Cardiovascular …, 2018 - academic.oup.com
Vascular calcification is associated with a significant increase in all-cause mortality and
atherosclerotic plaque rupture. Calcification has been determined to be an active process …

Coronary artery plaque characteristics associated with adverse outcomes in the SCOT-HEART study

MC Williams, AJ Moss, M Dweck, PD Adamson… - Journal of the American …, 2019 - jacc.org
Background Unlike most noninvasive imaging modalities, coronary computed tomography
angiography can characterize subtypes of atherosclerotic plaque. Objectives The purpose of …

Clinical utility of polygenic risk scores for coronary artery disease

D Klarin, P Natarajan - Nature Reviews Cardiology, 2022 - nature.com
Over the past decade, substantial progress has been made in the discovery of alleles
contributing to the risk of coronary artery disease. In addition to providing causal insights into …

The National Lipid Association scientific statement on coronary artery calcium scoring to guide preventive strategies for ASCVD risk reduction

CE Orringer, MJ Blaha, R Blankstein, MJ Budoff… - Journal of clinical …, 2021 - Elsevier
Abstract An Expert Panel of the National Lipid Association reviewed the evidence related to
the use of coronary artery calcium (CAC) scoring in clinical practice for adults seen for …

[HTML][HTML] National Lipid Association recommendations for patient-centered management of dyslipidemia: part 2

TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

Sex differences in myocardial and vascular aging

H Ji, AC Kwan, MT Chen, D Ouyang… - Circulation …, 2022 - Am Heart Assoc
It is well known that cardiovascular disease manifests differently in women and men. The
underlying causes of these differences during the aging lifespan are less well understood …

Prevalence of subclinical coronary artery disease in masters endurance athletes with a low atherosclerotic risk profile

A Merghani, V Maestrini, S Rosmini, AT Cox, H Dhutia… - Circulation, 2017 - Am Heart Assoc
Background: Studies in middle-age and older (masters) athletes with atherosclerotic risk
factors for coronary artery disease report higher coronary artery calcium (CAC) scores …