Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

Biochemical signals, such as growth factors, cytokines, and transcription factors are known
to play a crucial role in regulating a variety of cellular activities as well as maintaining the …

In recent years, the rate of implant failure has been increasing. Microbial infection was the
primary cause, and the main stages included bacterial adhesion, biofilm formation, and …

Regulating cell behavior using nanotopography has been widely implemented. To facilitate
cell adhesion, physical nanotopography is usually coated with adhesive proteins such as …

Peri-implantitis is a highly prevalent disease caused by bacterial plaque that results in
inflammation. The disease starts from the soft tissue and gradually spreads to the hard tissue …

Crystallization alters the characteristics of TiO2 nanosurfaces, which consequently
influences their bio-performance. In various biomedical applications, the anatase or rutile …

Block copolymer (BCP) self‐assembly has emerged as a feasible method for large‐scale
fabrication with remarkable precision–features that are not common for most of the …

Physical features on the biomaterial surface are known to affect macrophage cell shape and
phenotype, providing opportunities for the design of novel “immune-instructive” …

Therapeutic application in prevention and treatment of bone diseases, particularly
osteoporosis, has recently started to emerge for manganese dioxide (MnO 2) nanoparticles …