Association of vitamin D metabolism gene polymorphisms with autoimmunity: evidence in population genetic studies

AI Ruiz-Ballesteros, MR Meza-Meza… - International journal of …, 2020 - mdpi.com
A high prevalence of vitamin D (calcidiol) serum deficiency has been described in several
autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (AR), and …

Ultraviolet radiation, vitamin D and multiple sclerosis

RM Lucas, SN Byrne, J Correale… - Neurodegenerative …, 2015 - Taylor & Francis
There is compelling epidemiological evidence that the risk of developing multiple sclerosis
is increased in association with low levels of sun exposure, possibly because this is …

Association between vitamin D receptor (VDR) polymorphisms and the risk of multiple sclerosis (MS): an updated meta-analysis

D Imani, B Razi, M Motallebnezhad, R Rezaei - BMC neurology, 2019 - Springer
Background The association between the Vitamin D Receptor (VDR) gene polymorphism
and the risk of Multiple sclerosis (MS) has been evaluated in several researches. However …

Association of vdr, cyp27b1, cyp24a1 and mthfr gene polymorphisms with oral lichen planus risk

B Kujundzic, K Zeljic, G Supic, M Magic… - Clinical oral …, 2016 - Springer
Objectives The current study investigated the association between VDR EcoRV
(rs4516035), FokI (rs2228570), ApaI (rs7975232) and TaqI (rs731236), CYP27B1 …

Association between polymorphisms in the vitamin D receptor and susceptibility to multiple sclerosis

BC Díez, C Pérez-Ramírez… - Pharmacogenetics …, 2021 - journals.lww.com
Objectives Multiple sclerosis (MS) is a neurodegenerative chronic inflammatory. Mutations in
the vitamin D receptor (VDR) gene can substantially affect serum vitamin D levels or alter its …

Association between VDR polymorphisms and multiple sclerosis: systematic review and updated meta-analysis of case-control studies

YJ Zhang, L Zhang, SY Chen, GJ Yang, XL Huang… - Neurological …, 2018 - Springer
Vitamin D receptor (VDR) polymorphisms have been inconsistently investigated in multiple
sclerosis (MS). However, published studies demonstrated differences concerning design …

Association between vitamin D receptor gene polymorphisms with childhood temporal lobe epilepsy

P Jiang, WY Zhu, X He, MM Tang, RL Dang… - International Journal of …, 2015 - mdpi.com
Vitamin D (VD) is implicated in multiple aspects of human physiology and vitamin D receptor
(VDR) polymorphisms are associated with a variety of neuropsychiatric disorders. Although …

Vitamin D receptor gene polymorphisms are associated with multiple sclerosis in Mexican adults

VH Bermúdez-Morales, G Fierros, RL Lopez… - Journal of …, 2017 - Elsevier
Background Multiple sclerosis (MS) is the most prevalent autoimmune inflammatory
demyelinating disease of the central nervous system (CNS) in young adults. More than 50 …

The vitamin D receptor gene FokI polymorphism and Multiple Sclerosis in a Northern Portuguese population

A Bettencourt, D Boleixa, AL Guimarães, B Leal… - Journal of …, 2017 - Elsevier
Abstract Background The cause of Multiple Sclerosis (MS) remains poorly understood, but it
is widely believed to be an autoimmune disease occurring in genetically susceptible …

The impact of five VDR polymorphisms on multiple sclerosis risk and progression: a case-control and genotype-phenotype study

P Křenek, Y Benešová, J Bienertová-Vašků… - Journal of Molecular …, 2018 - Springer
Vitamin D receptor polymorphisms have been the target of many studies focusing on
multiple sclerosis. However, previously reported results have been inconclusive. The …